Evidence map›Paper›PMID 28094974›Full record

ArticleACS chemical neuroscience2017

Monitoring Dopamine Responses to Potassium Ion and Nomifensine by in Vivo Microdialysis with Online Liquid Chromatography at One-Minute Resolution.

Khanh T Ngo, Erika L Varner, Adrian C Michael, Stephen G Weber

Open access · greenAbstract read
In one paragraph

Article in ACS chemical neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 67 citations in OpenAlex.

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  11. MnFrontiers in bioengineering and biotechnology · 2022
    Article
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  15. Article
  16. Evaluation of electrochemical methods for tonic dopamine detectionTrends in analytical chemistry : TRAC · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. A rotating operant chamber for use with microdialysis.Journal of neuroscience methods · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Khanh T NgoDepartment of Chemistry, University of Pittsburgh , Pittsburgh, Pennsylvania 15260, United States.ORCID 0000-0003-2325-5236
Erika L VarnerDepartment of Chemistry, University of Pittsburgh , Pittsburgh, Pennsylvania 15260, United States.
Adrian C MichaelDepartment of Chemistry, University of Pittsburgh , Pittsburgh, Pennsylvania 15260, United States.
Stephen G WeberDepartment of Chemistry, University of Pittsburgh , Pittsburgh, Pennsylvania 15260, United States.ORCID 0000-0002-7970-2632
University of Pittsburgh · US

Funding

Fast Online Microdialysis/Liquid Chromatography for Monoamine NeurotransmittersR01MH104386 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WEBER, STEPHEN G. · 2014 to 2017
$1.3M
NIMH NIH HHS R01 MH104386
6 · The paper itself

Abstract

Recently, our laboratory has demonstrated the technical feasibility of monitoring dopamine at 1 min temporal resolution with microdialysis and online liquid chromatography. Here, we monitor dopamine in the rat striatum during local delivery of high potassium/low sodium or nomifensine in awake-behaving rats. Microdialysis probes were implanted and perfused continuously with or without dexamethasone in the perfusion fluid for 4 days. Dexamethasone is an anti-inflammatory agent that exhibits several positive effects on the apparent health of the brain tissue surrounding microdialysis probes. Dopamine was monitored 1 or 4 days after implantation under basal conditions, during 10 min applications of 60 mM or 100 mM K

Indexed as

AnimalsBrainChromatography, LiquidDopamineDopamine Uptake InhibitorsElectric StimulationEvoked PotentialsMaleMicrodialysisNomifensineOnline SystemsPotassiumRatsRats, Sprague-DawleyWakefulnessDopamineDopamine Uptake InhibitorsNomifensinePotassiumCapillary liquid chromatographychronic implantationdexamethasoneelectrochemical detectionprincipal component analysis

Identifiers

PMID28094974
PMCPMC5464422
OpenAlexW2579140559

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.