Evidence map›Paper›PMID 28094448›Full record

ReviewMedicinal research reviews2018

Human Antimicrobial Peptides in Bodily Fluids: Current Knowledge and Therapeutic Perspectives in the Postantibiotic Era.

Paulo Bastos, Fábio Trindade, João da Costa, Rita Ferreira, Rui Vitorino

Abstract readReview
In one paragraph

Review in Medicinal research reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
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  4. Article
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  9. Review
  10. Combining the Peptide RWQWRWQWR and an Ethanolic Extract ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  11. Article
  12. Review
  13. Calcitermin-Loaded Smart Gels Activity againstGels (Basel, Switzerland) · 2023
    Article
  14. Circulating Peptidome Is Strongly Altered in COVID-19 Patients.International journal of environmental research and public health · 2023
    Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Real-Time Fluorescence Microscopy on LivingInternational journal of molecular sciences · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Paulo BastosDepartment of Medical Sciences, iBiMED-Institute for Research in Biomedicine, University of Aveiro, Aveiro, Portugal.
Fábio TrindadeDepartment of Medical Sciences, iBiMED-Institute for Research in Biomedicine, University of Aveiro, Aveiro, Portugal.
João da CostaDepartment of Chemistry, CESAM, University of Aveiro, Aveiro, Portugal.
Rita FerreiraDepartment of Chemistry, QOPNA, Mass Spectrometry Center, University of Aveiro, Aveiro, Portugal.
Rui VitorinoDepartment of Medical Sciences, iBiMED-Institute for Research in Biomedicine, University of Aveiro, Aveiro, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial peptides (AMPs) are an integral part of the innate immune defense mechanism of many organisms. Due to the alarming increase of resistance to antimicrobial therapeutics, a growing interest in alternative antimicrobial agents has led to the exploitation of AMPs, both synthetic and isolated from natural sources. Thus, many peptide-based drugs have been the focus of increasing attention by many researchers not only in identifying novel AMPs, but in defining mechanisms of antimicrobial peptide activity as well. Herein, we review the available strategies for the identification of AMPs in human body fluids and their mechanism(s) of action. In addition, an overview of the distribution of AMPs across different human body fluids is provided, as well as its relation with microorganisms and infectious conditions.

Indexed as

AnimalsAntimicrobial Cationic PeptidesBody FluidsHumansAntimicrobial Cationic Peptidesantibacterialantifungalantiviralhuman antimicrobial peptideshuman biological fluidspeptidomics

Identifiers

PMID28094448
PMCPMC7168463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.