Evidence map›Paper›PMID 28094303›Full record

ArticleScientific reports2017

Genetic Polymorphisms of rs3077 and rs9277535 in HLA-DP associated with Systemic lupus erythematosus in a Chinese population.

Junlong Zhang, Wenli Zhan, Bin Yang, Anning Tian, Lin Chen, Yun Liao, Yongkang Wu, Bei Cai, Lanlan Wang

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Junlong ZhangDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Wenli ZhanDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Bin YangDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Anning TianDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Lin ChenDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Yun LiaoDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Yongkang WuDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Bei CaiDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Lanlan WangDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
West China Hospital of Sichuan University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the SLE risk gene loci of HLA-DR and HLA-DQ within the major histocompatibility complex (MHC) region has been gradually revealed by recent Genome-Wide Association studies (GWAS), the association of HLA-DP polymorphisms with SLE was minimally reported. Considering that the variants in rs3077 and rs9277535 in the HLA-DP region could influence the immune response by affecting antigen presentation of HLA class II molecules to CD4

Indexed as

GenotypeAdultChinaCytokinesFemaleGene FrequencyGenetic Predisposition to DiseaseHLA-DP AntigensHumansInflammation MediatorsLupus Erythematosus, SystemicMaleMiddle AgedPolymorphism, Single NucleotideSkinVasculitisCytokinesHLA-DP AntigensInflammation Mediators

Identifiers

PMID28094303
PMCPMC5240340
OpenAlexW2578610724

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.