Trial reportKidney international2017
Patients receiving frequent hemodialysis have better health-related quality of life compared to patients receiving conventional hemodialysis.
Trial report in Kidney international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Interventions for fatigue in people with kidney failure requiring dialysis.The Cochrane database of systematic reviews · 2023Pooled it
- Renal Association Clinical Practice Guideline on Haemodialysis.BMC nephrology · 2019Guideline
- Effect of hemodiafiltration on measured physical activity: primary results of the HDFIT randomized controlled trial.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021Trial
- Post-Dialysis Syndrome: A Narrative Review.Kidney360 · 2026Review
- Pain Interference in Maintenance Hemodialysis: A Single-Center Cross-Sectional Study Using the Pain Effects Scale (PES).Journal of clinical medicine · 2026Article
- The Association of Serum Bicarbonate With Psychological and Physical Health-Related Quality of Life in Patients Receiving Maintenance Hemodialysis: A Secondary Analysis of the Frequent Hemodialysis Network Daily Trial.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2026Article
- Efficacy of slow daily home hemodialysis with internal convection on removal of uremic toxins using the Physidia S3 monitor.Scientific reports · 2025Article
- Quality of life trajectories for different dialysis modalities-a nationwide study.Clinical kidney journal · 2025Article
- Bringing the end-stage kidney disease life plan home.Current opinion in nephrology and hypertension · 2025Article
- Article
- Pay-for-performance programs effectiveness in healthcare: the case of the end-stage renal disease quality incentive program.The European journal of health economics : HEPAC : health economics in prevention and care · 2024Article
- The trajectory of a range of commonly captured symptoms with standard care in people with kidney failure receiving haemodialysis: consideration for clinical trial design.BMC nephrology · 2023Article
- Fatigue in Patients Receiving Maintenance Hemodialysis: A Review.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023Review
- Post-dialysis recovery time in ESRD patients receiving more frequent hemodialysis in skilled nursing facilities.Hemodialysis international. International Symposium on Home Hemodialysis · 2022Article
- Patient Preferences for Longer or More Frequent In-Center Hemodialysis Regimens: A Multicenter Discrete Choice Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2022Article
- Clinical Outcomes With Medium Cut-Off Versus High-Flux Hemodialysis Membranes: A Systematic Review and Meta-Analysis.Canadian journal of kidney health and disease · 2022Article
- Knowledge Requirements and Unmet Needs of Informal Caregivers of Patients with End-Stage Kidney Disease (ESKD) Receiving Haemodialysis: A Narrative Review.Healthcare (Basel, Switzerland) · 2021Review
- Framing Cause-Effect Relationship of Acute Coronary Syndrome in Patients with Chronic Kidney Disease.Diagnostics (Basel, Switzerland) · 2021 · on this mapReview
- Contextualizing the FHN Nocturnal Trial a Decade Later: How Nocturnal Home Hemodialysis Is Performed Matters to Outcomes.Clinical journal of the American Society of Nephrology : CJASN · 2021Article
- A Narrative Review of Management Strategies for Common Symptoms in Advanced CKD.Kidney international reports · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Most patients with end-stage kidney disease value their health-related quality of life (HRQoL) and want to know how it will be affected by their dialysis modality. We extended the findings of two prior clinical trial reports to estimate the effects of frequent compared to conventional hemodialysis on additional measures of HRQoL. The Daily Trial randomly assigned 245 patients to receive frequent (six times per week) or conventional (three times per week) in-center hemodialysis. The Nocturnal Trial randomly assigned 87 patients to receive frequent nocturnal (six times per week) or conventional (three times per week) home hemodialysis. All patients were on conventional hemodialysis prior to randomization, with an average feeling thermometer score of 70 to 75 (a visual analog scale from 0 to 100 where 100 is perfect health), an average general health scale score of 40 to 47 (a score from 0 to 100 where 100 is perfect health), and an average dialysis session recovery time of 2 to 3 hours. Outcomes are reported as the between-treatment group differences in one-year change in HRQoL measures and analyzed using linear mixed effects models. After one year in the Daily Trial, patients assigned to frequent in-center hemodialysis reported a higher feeling thermometer score, better general health, and a shorter recovery time after a dialysis session compared to standard thrice-weekly dialysis. After one year in the Nocturnal Trial, patients assigned to frequent home hemodialysis also reported a shorter recovery time after a dialysis session, but no statistical difference in their feeling thermometer or general health scores compared to standard home dialysis schedules. Thus, patients receiving day or nocturnal hemodialysis on average recovered approximately one hour earlier from a frequent compared to conventional hemodialysis session. Patients treated in an in-center dialysis facility reported better HRQoL with frequent compared to conventional hemodialysis.
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What OpenQuestion holds
Registered trials
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