ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2017
Enhancement of visual cortex plasticity by dark exposure.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Interactions between excitatory neurons and parvalbumin interneurons in V1 underlie neural mechanisms of amblyopia and visual stimulation treatment.Communications biology · 2024Article
- Prenatal environment is associated with the pace of cortical network development over the first three years of life.Nature communications · 2024Article
- Perineuronal Net Microscopy: From Brain Pathology to Artificial Intelligence.International journal of molecular sciences · 2024Review
- Sequential maturation of stimulus-specific adaptation in the mouse lemniscal auditory system.Science advances · 2024Article
- Low frequency repetitive transcranial magnetic stimulation promotes plasticity of the visual cortex in adult amblyopic rats.Frontiers in neuroscience · 2023Article
- Human deprivation amblyopia: treatment insights from animal models.Frontiers in neuroscience · 2023Article
- Article
- Refinements to rodent head fixation and fluid/food control for neuroscience.Journal of neuroscience methods · 2022Review
- Binocular visual experience drives the maturation of response variability and reliability in the visual cortex.iScience · 2022Article
- Visual Cortex Engagement in Retinitis Pigmentosa.International journal of molecular sciences · 2021Article
- Dark Rearing Promotes the Recovery of Visual Cortical Responses but Not the Morphology of Geniculocortical Axons in Amblyopic Cat.Frontiers in neural circuits · 2021Article
- Monocular Deprivation Affects Visual Cortex Plasticity Through cPKCγ-Modulated GluR1 Phosphorylation in Mice.Investigative ophthalmology & visual science · 2020Article
- Neuregulin and ErbB expression is regulated by development and sensory experience in mouse visual cortex.The Journal of comparative neurology · 2020Article
- Visual Experience Regulates the Intrinsic Excitability of Visual Cortical Neurons to Maintain Sensory Function.Cell reports · 2019Article
- Plasticity in Adult Mouse Visual Cortex Following Optic Nerve Injury.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Modification of Peak Plasticity Induced by Brief Dark Exposure.Neural plasticity · 2019Article
- Spatial Memory Engram in the Mouse Retrosplenial Cortex.Current biology : CB · 2018Article
- Article
- Integrating Hebbian and homeostatic plasticity: introduction.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Article
- Leveraging neural plasticity for the treatment of amblyopia.Survey of ophthalmologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Dark rearing is known to delay the time course of the critical period for ocular dominance plasticity in the visual cortex. Recent evidence suggests that a period of dark exposure (DE) may enhance or reinstate plasticity even after closure of the critical period, mediated through modification of the excitatory-inhibitory balance and/or removal of structural brakes on plasticity. Here, we investigated the effects of a week of DE on the recovery from a month of monocular deprivation (MD) in the primary visual cortex (V1) of juvenile mice. Optical imaging of intrinsic signals revealed that ocular dominance in V1 of mice that had received DE recovered slightly more quickly than of mice that had not, but the level of recovery after three weeks was similar in both groups. Two-photon calcium imaging showed no significant difference in the recovery of orientation selectivity of excitatory neurons between the two groups. Parvalbumin-positive (PV+) interneurons exhibited a smaller ocular dominance shift during MD but again no differences in subsequent recovery. The percentage of PV+ cells surrounded by perineuronal nets, a structural brake on plasticity, was lower in mice with than those without DE. Overall, DE causes a modest enhancement of mouse visual cortex plasticity.This article is part of the themed issue 'Integrating Hebbian and homeostatic plasticity'.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.