Evidence map›Paper›PMID 28093552›Full record

ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2017

Integrating Hebbian and homeostatic plasticity: the current state of the field and future research directions.

Tara Keck, Taro Toyoizumi, Lu Chen, Brent Doiron, Daniel E Feldman, Kevin Fox, Wulfram Gerstner, Philip G Haydon, Mark Hübener, Hey-Kyoung Lee and 7 more

Abstract readConference Proceedings
In one paragraph

Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

110 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Cell-Type-Specific Synaptic Scaling Mechanisms Differentially Contribute to Associative Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  3. Article
  4. Homeostatic Plasticity Enables Stable yet Tunable Neuronal Assemblies.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Mechanistic explanation of neuroplasticity using equivalent circuits.Frontiers in computational neuroscience · 2026
    Article
  10. Article
  11. Review
  12. Sleeping upside-down: Knockdown of a sleep-associated gene induces daytime sleep in the jellyfishProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

50 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Tara KeckDepartment of Neuroscience, Physiology and Pharmacology, University College London, London, UK t.keck@ucl.ac.uk.ORCID 0000-0001-6623-1037
Taro ToyoizumiRIKEN Brain Science Institute, Wako, Japan.ORCID 0000-0001-5444-8829
Lu ChenDepartment of Neurosurgery, Stanford University, Stanford, CA, USA.
Brent DoironDepartment of Mathematics, University of Pittsburgh, Pittsburgh, PA, USA.
Daniel E FeldmanDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, USA.ORCID 0000-0003-4646-8170
Kevin FoxDivision of Neuroscience, University of Cardiff, Cardiff, Wales, UK.
Wulfram GerstnerBrain Mind Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Philip G HaydonTufts University School of Medicine, Medford, MA, USA.
Mark HübenerDepartment of Cellular and Systems Neuroscience, Max Planck Institute of Neurobiology, Martinsried, Bayern, Germany.
Hey-Kyoung LeeThe Zanvyl Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-5554-983X
John E LismanDepartment of Biology, Brandeis University, Waltham, MA, USA.ORCID 0000-0003-2676-225X
Tobias RoseDepartment of Cellular and Systems Neuroscience, Max Planck Institute of Neurobiology, Martinsried, Bayern, Germany.ORCID 0000-0002-7156-4714
Frank SengpielDepartment of Neuroscience, Physiology and Pharmacology, University College London, London, UK.ORCID 0000-0002-7060-1851
David StellwagenCentre for Research in Neuroscience, McGill University, Montreal, Quebec, Canada.ORCID 0000-0003-3509-103X
Michael P StrykerSandler Neurosciences Center, University of California, San Francisco, CA, USA.ORCID 0000-0003-1546-5831
Gina G TurrigianoDepartment of Biology, Brandeis University, Waltham, MA, USA.
Mark C van RossumSchool of Informatics, University of Edinburgh, Edinburgh, UK.ORCID 0000-0001-6525-6814

Funding

Rapid-Prototyping and Design CoreP30EY002162 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LAMBA, DEEPAK ASHOK · 1985 to 2024
$16.8M
Global Synpatic Plasticity Mechanisms in Visual CortexR01EY014882 · NEI · UNIV OF MARYLAND, COLLEGE PARK · PI Hey-Kyoung Lee · 2004 to 2026
$7.9M
DEVELOPMENT &PLASTICITY OF THE VISUAL SYSTEMR01EY002874 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STRYKER, MICHAEL P · 1986 to 2022
$6.4M
ASTROCYTE/NEURON SIGNALINGR01NS037585 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI HAYDON, PHILIP G · 1998 to 2019
$4.5M
Developmental Pathophysiology of Synapses in a Mouse Model of Fragile X SyndromeR01HD084215 · NICHD · STANFORD UNIVERSITY · PI CHEN, LU · 2014 to 2018
$3.3M
Inhibitory mechanisms for sensory map plasticity in cerebral cortex.R01NS073912 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI FELDMAN, DANIEL · 2011 to 2015
$1.6M
CRCNS: Neural signals that maintain/refresh LTP and memoryR01DA043195 · NIDA · BRANDEIS UNIVERSITY · PI GRIFFITH, LESLIE C · 2017 to 2019
$1.1M
Medical Research Council MR/N003896/1NEI NIH HHS P30 EY002162NEI NIH HHS R01 EY002874NEI NIH HHS R01 EY014882NICHD NIH HHS R01 HD084215NIDA NIH HHS R01 DA043195NINDS NIH HHS R01 NS037585NINDS NIH HHS R01 NS073912
6 · The paper itself

Abstract

We summarize here the results presented and subsequent discussion from the meeting on Integrating Hebbian and Homeostatic Plasticity at the Royal Society in April 2016. We first outline the major themes and results presented at the meeting. We next provide a synopsis of the outstanding questions that emerged from the discussion at the end of the meeting and finally suggest potential directions of research that we believe are most promising to develop an understanding of how these two forms of plasticity interact to facilitate functional changes in the brain.This article is part of the themed issue 'Integrating Hebbian and homeostatic plasticity'.

Indexed as

HomeostasisNeuronal PlasticityAnimalsBrainHumansHebbian plasticityhomeostatic mechanismstheoretical modelling

Identifiers

PMID28093552
PMCPMC5247590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.