ArticleDisease models & mechanisms2017
Vertical sleeve gastrectomy reduces blood pressure and hypothalamic endoplasmic reticulum stress in mice.
Article in Disease models & mechanisms, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
- Ablation ofScience (New York, N.Y.) · 2026Article
- Endoplasmic Reticulum Stress: A Novel Target for the Prevention and Treatment of Hypertension and Its Related Diseases.Journal of cellular and molecular medicine · 2025Review
- Beyond weight loss: exploring the neurological ramifications of altered gut microbiota post-bariatric surgery.Journal of translational medicine · 2025Review
- Vertical Sleeve Gastrectomy Reduces Gut Luminal Deoxycholic Acid Concentrations in Mice.Obesity surgery · 2024Article
- Change in medial frontal cerebral metabolite concentrations following bariatric surgery.NMR in biomedicine · 2023Article
- Do bariatric patient's in rural areas achieve comparative weight loss as national average? single center experience in appalachia west virginia.Surgical endoscopy · 2022Article
- The potential impact of a probiotic: Akkermansia muciniphila in the regulation of blood pressure-the current facts and evidence.Journal of translational medicine · 2022Review
- Exploring the Relationship Between Bariatric Surgery and Inflammatory Bowel Disease: A Systematic Review.Crohn's & colitis 360 · 2022Article
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- Alteration of Gut Microbiota Relates to Metabolic Disorders in Primary Aldosteronism Patients.Frontiers in endocrinology · 2021Article
- Role of the Autonomic Nervous System in Mechanism of Energy and Glucose Regulation Post Bariatric Surgery.Frontiers in neuroscience · 2021Review
- Obesity, Hypertension, and Bariatric Surgery.Current hypertension reports · 2020Review
- Surgical Mouse Models of Vertical Sleeve Gastrectomy and Roux-en Y Gastric Bypass: a Review.Obesity surgery · 2019Review
- Elevated plasma endothelin-1 is associated with reduced weight loss post vertical sleeve gastrectomy.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2019Article
- Impaired Autonomic Nervous System-Microbiome Circuit in Hypertension.Circulation research · 2019Review
- Could de-stressing the brain be the solution for long-term weight loss?Cell stress · 2019Article
- Article
- A Murine Model of Vertical Sleeve Gastrectomy.Journal of visualized experiments : JoVE · 2017Article
- Bile acids at the cross-roads of gut microbiome-host cardiometabolic interactions.Diabetology & metabolic syndrome · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 2 countries.
Funding
Abstract
Bariatric surgery, such as vertical sleeve gastrectomy (VSG), causes remarkable improvements in cardiometabolic health, including hypertension remission. However, the mechanisms responsible remain undefined and poorly studied. Therefore, we developed and validated the first murine model of VSG that recapitulates the blood pressure-lowering effect of VSG using gold-standard radiotelemetry technology. We used this model to investigate several potential mechanisms, including body mass, brain endoplasmic reticulum (ER) stress signaling and brain inflammatory signaling, which are all critical contributors to the pathogenesis of obesity-associated hypertension. Mice fed on a high-fat diet underwent sham or VSG surgery and radiotelemeter implantation. Sham mice were fed
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.