Evidence map›Paper›PMID 28093477›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Differential Presynaptic ATP Supply for Basal and High-Demand Transmission.

Courtney Sobieski, Michael J Fitzpatrick, Steven J Mennerick

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Mitochondrial CaNature metabolism · 2026
    Article
  5. Mitochondrial CaBiomolecules · 2026
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Dopamine Release Neuroenergetics in Mouse Striatal Slices.International journal of molecular sciences · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Courtney SobieskiDepartment of Psychiatry.ORCID 0000-0002-4171-4216
Michael J FitzpatrickDepartment of Psychiatry.ORCID 0000-0001-7663-2635
Steven J MennerickDepartment of Psychiatry, menneris@wustl.edu.ORCID 0000-0003-0868-0664
Gaertner (United States) · USWashington University in St. Louis · US

Funding

CONTROL OF SYNAPTIC GLUTAMATE RELEASER01MH078823 · NIMH · WASHINGTON UNIVERSITY · PI MENNERICK, STEVEN J · 2006 to 2015
$3.2M
RECEPTOR POPULATIONS UNDERLYING TONIC GABA CURRENTS IN HIPPOCAMPUSR21MH099658 · NIMH · WASHINGTON UNIVERSITY · PI MENNERICK, STEVEN J · 2013 to 2014
$418k
NEUROSTEROIDS AND ANXIETY RELATED NETWORK FUNCTIONR21MH104506 · NIMH · WASHINGTON UNIVERSITY · PI MENNERICK, STEVEN J · 2014 to 2015
$406k
Candidate-based and Discovery-based Analysis of Astrocytes and Glutamate NeurotransmissionF31MH106198 · NIMH · WASHINGTON UNIVERSITY · PI SOBIESKI, COURTNEY · 2015 to 2016
$52k
NIMH NIH HHS F31 MH106198NIMH NIH HHS R01 MH078823NIMH NIH HHS R21 MH099658NIMH NIH HHS R21 MH104506
6 · The paper itself

Abstract

The relative contributions of glycolysis and oxidative phosphorylation to neuronal presynaptic energy demands are unclear. In rat hippocampal neurons, ATP production by either glycolysis or oxidative phosphorylation alone sustained basal evoked synaptic transmission for up to 20 min. However, combined inhibition of both ATP sources abolished evoked transmission. Neither action potential propagation failure nor depressed Ca

Indexed as

Action PotentialsAdenosine TriphosphateAnimalsAnimals, NewbornAstrocytesCells, CulturedEndocytosisEnzyme InhibitorsGlycolysisHippocampusNeuronsNeurotransmitter AgentsPatch-Clamp TechniquesPhosphorylationPotassium ChloridePresynaptic TerminalsAdenosine TriphosphateEnzyme InhibitorsNeurotransmitter AgentsPotassium Chlorideastrocyteglutamateglycolysisneuroenergeticspresynaptic

Identifiers

PMID28093477
PMCPMC5320616
OpenAlexW2575996993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.