Evidence map›Paper›PMID 28093440›Full record

ArticleBMJ open2017

Cross-sectional, descriptive study of Chagas disease among citizens of Bolivian origin living in Munich, Germany.

Miriam Navarro, Nicole Berens-Riha, Stefan Hohnerlein, Peter Seiringer, Charlotte von Saldern, Sarah Garcia, Teresa Blasco-Hernández, Bárbara Navaza, Jonathan Shock, Gisela Bretzel and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
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  7. Chagas disease and perceived quality of life: a cross-sectional study.Revista da Sociedade Brasileira de Medicina Tropical · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 4 countries.

Miriam NavarroFundación Mundo Sano, Madrid, Spain.
Nicole Berens-RihaDepartment of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich (LMU), Munich, Germany.
Stefan HohnerleinDepartment of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich (LMU), Munich, Germany.
Peter SeiringerDepartment of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich (LMU), Munich, Germany.
Charlotte von SaldernDepartment of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich (LMU), Munich, Germany.
Sarah GarciaDepartment of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich (LMU), Munich, Germany.
Teresa Blasco-HernándezCentro Nacional de Medicina Tropical (Instituto de Salud Carlos III), Madrid, Spain.
Bárbara NavazaFundación Mundo Sano, Madrid, Spain.
Jonathan ShockThe Laboratory for Quantum Gravity & Strings, Department of Mathematics and Applied Mathematics, University of Cape Town, Cape Town, South Africa.
Gisela BretzelDepartment of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich (LMU), Munich, Germany.
Michael HoelscherDepartment of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich (LMU), Munich, Germany.
Thomas LöscherDepartment of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich (LMU), Munich, Germany.
Pedro Albajar-ViñasDepartment of Control of Neglected Tropical Diseases, World Health Organization (WHO), Geneva, Switzerland.
Michael PritschDepartment of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich (LMU), Munich, Germany.
Ludwig-Maximilians-Universität München · DEGerman Center for Infection Research · DECentro Nacional de Medicina Tropical · ESUniversity of Cape Town · ZAWorld Health Organization · CH

Funding

World Health Organization 001
6 · The paper itself

Abstract

purposeChagas disease (CD) has become a global health issue mainly due to migration. Germany lacks surveillance data and is home to a large Latin American immigrant population. Recognising that Bolivia is the country with the highest CD prevalence in Latin America, this cross-sectional, descriptive pilot study investigated CD and associated factors among citizens of Bolivian origin living in Munich, Germany.

methodsParticipants completed a questionnaire in order to collect socioeconomic and health-related data. In addition, serology was performed. In case of positive serological tests, PCR diagnostic and clinical staging together with disease management was initiated. Qualitative research was conducted to identify personal and community barriers as well as strategies to increase CD awareness among the population at risk.

resultsBetween June 2013 and June 2014, 43 people from Bolivia (or descendants) were enrolled. A total of 9.3% (4/43), of whom two women were of childbearing age, tested seropositive (ELISA and IFAT), and one also by PCR. For 2/4 positive participants, clinical evaluation was performed and the indeterminate form of CD was diagnosed. Knowledge about CD symptoms and ways of transmission were completely absent among 55.8% (24/43, 2/4 with CD) and 30.2% (13/43, 1/4 with CD) of participants, respectively. A total of 27.9% (12/43, 0/4 with CD) of participants had donated blood prior to the study, whereas 62.8% (27/43, 3/4 with CD) were motivated to donate blood in the future. The qualitative research identified lack of knowledge as well as stigma and fears related to CD.

conclusionsDespite the small number of participants, the prevalence of CD as well as the potential risk of non-vectorial transmission was alarming. Campaigns adapted for Latin American migrants as well as control strategies should be developed and put in place in order to prevent non-vectorial transmission and actively detect cases of CD in Germany.

Indexed as

AdolescentAdultAgedBoliviaChagas DiseaseChildCross-Sectional StudiesEmigrants and ImmigrantsEnzyme-Linked Immunosorbent AssayFemaleGermanyHumansMaleMiddle AgedPilot ProjectsPolymerase Chain ReactionChagas DiseaseGermanyMigrationTrypanosoma cruzi

Identifiers

PMID28093440
PMCPMC5253600
OpenAlexW2577617818

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.