ArticleBMJ open2017
Risk for metabolic diseases in normal weight individuals with visceral fat accumulation: a cross-sectional study in Japan.
Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04175886 (Effects of Tofacitinib on Body Composition, Bone Mineral Density and Bone Marrow Adiposity in Patients With Rheumatoid Arthritis), which is not on this map. Cited by 51 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Tofacitinib on Body Composition, Bone Mineral Density and Bone Marrow Adiposity in Patients With Rheumatoid Arthritis: the TOFAT Project
Who cites it
51 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Plasma Lipoprotein(a) Levels in Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023Pooled it
- Effect of Tirzepatide on Health-Related Quality of Life in Japanese Patients With Obesity Disease: Patient-Reported Outcomes From the SURMOUNT-J Study.Diabetes, obesity & metabolism · 2026Trial
- Association of baseline characteristics with clinical outcomes of tirzepatide treatment in Japanese patients with obesity disease: A subgroup analysis of the SURMOUNT-J trial.Diabetes, obesity & metabolism · 2026Trial
- Impact of diet intervention on visceral adipose tissue and hepatic fat in patients with obesity or type 2 diabetes: a randomized trial.Scientific reports · 2024Trial
- Clinical Impact of Preoperative Obesity on Living-Donor Kidney Transplant Recipients in Japan: A Multicenter Experience.Journal of clinical medicine · 2026Article
- Assessment of Quality of Life Among Laparoscopic Sleeve Gastrectomy Patients in the Aseer Region, Saudi Arabia.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Genetic impact of central adiposity on systolic blood pressure in females: interaction and mediation by TG/HDL-C, HbA1c, and uric acid across BMI categories.International journal of obesity (2005) · 2025Article
- Article
- Triglyceride-Glucose-Based Anthropometric Indices for Predicting Incident Cardiovascular Disease: Relative Fat Mass (RFM) as a Robust Indicator.Nutrients · 2025Article
- Nonlinear Association Between the Visceral-to-Subcutaneous Fat Area Ratio and the Risk of Hypertension in Prediabetic Individuals: Evidence From a Large-Scale Health Screening Dataset in China.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Association between visceral fat area and metabolic syndrome in individuals with normal body weight: insights from a Chinese health screening dataset.Lipids in health and disease · 2025Article
- The weight-adjusted-waist index predicts all-cause and cardiovascular mortality in hypertension.Frontiers in cardiovascular medicine · 2025Article
- Visceral obesity augments prescription use: An analysis of the cross-sectional study of NHANES 2011-2018.PloS one · 2025Article
- Effects of a Six-Month Physical Activity Program on Health Risk Factors and Body Composition Among Overweight and Obese Middle-Aged Adults.Healthcare (Basel, Switzerland) · 2024Article
- Association between weight-adjusted waist index and testosterone deficiency in adult American men: findings from the national health and nutrition examination survey 2013-2016.BMC public health · 2024Article
- Sex and age difference in associations between anthropometric indices and hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Metabolic Abnormalities Following Tirzepatide Monotherapy in Japanese Patients with Type 2 Diabetes: A Phase 3 SURPASS J-mono Post Hoc Analysis.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024Article
- Prevalence of Metabolic Syndrome in Patients with Type 2 Diabetes in Japan: A Retrospective Cross-Sectional Study.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024Article
- A positive relationship between weight-adjusted waist index and non-alcoholic fatty liver disease: a study on US adolescents.Frontiers in medicine · 2024Article
- Sex differences in waist circumference obesity and eating speed: a cross-sectional study of Japanese people with normal body mass index.Frontiers in nutrition · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the association between visceral fat area (VFA) and metabolic syndrome (Mets) among normal weight Japanese.
designA cross-sectional study.
settingThe health check-up centre of the Takeda Hospital group in Kyoto, Japan.
methodsThis study involved 1674 men and 1448 women aged 30-74 years who underwent medical check-ups in 2012 in the health check-up centre. They were stratified by Body Mass Index (BMI cut-off for obesity is set at 23.0 kg/m
resultsParticipants in the 2nd to 4th VFA quartiles had significantly higher clustering risks; ORs were 3.4 (1.5 to 8.0), 6.3 (2.8 to 14.2) and 9.3 (4.2 to 20.7) for normal weight participants, and 1.7 (1.2 to 2.6), 2.6 (1.8 to 3.9) and 6.0 (4.1 to 8.8) for higher weight participants, respectively. The ORs of the 4th VFA quartile for Mets components were significantly higher; ORs for normal weight participants were 2.1 (1.5 to 3.0) (high blood pressure), 2.4 (1.4 to 4.2) (high FBG), 5.2 (2.1 to 12.9) (low HDL-C) and 12.0 (5.7 to 25.3) (high triglycerides), and higher weight participants were 3.9 (2.8 to 5.5), 4.1 (2.8 to 6.2), 3.9 (2.2 to 6.9) and 5.0 (3.4 to 7.4), respectively.
conclusionsAmong participants with normal weight, as well as those of higher weight, dose-dependent responses were observed between VFA and risk for Mets components and the clustering among Japanese adults. VFA may be useful information for interventions to improve metabolic risk factors in people with normal weight.
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