SynthesisBMC surgery2017
Albumin and surgical site infection risk in orthopaedics: a meta-analysis.
Synthesis in BMC surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 2 syntheses or guidelines pooled it, 146 citations in OpenAlex.
- A Systematic Review of Predictor Composition, Outcomes, Risk of Bias, and Validation of COVID-19 Prognostic Scores.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Pooled it
- The Impact of Hypoalbuminemia on Postoperative Complications in Patients Undergoing Shoulder Arthroplasty: A Meta-Analysis.The journal of nutrition, health & aging · 2023Pooled it
- From Serum to Surgery: The Significance of Albumin in Preoperative Risk Stratification-An Analysis of 200,015 Plastic Surgery Patients.Aesthetic plastic surgery · 2026Article
- Association between preoperative hypoalbuminemia and surgical site infection in abdominal surgery: a systematic review and meta-analysis.Patient safety in surgery · 2026Review
- Association between preoperative controlling nutritional status score and surgical site infection following instrumented posterior lumbar interbody fusion.Frontiers in surgery · 2026Article
- Determinants of Dehiscence and Wound Infections After Open Reduction and Internal Fixation of Femoral Shaft and Subtrochanteric fractures.Orthopedic reviews · 2026Article
- Mechanistic approach to laser-induced oxidative stress and apoptosis in breast cancer cells using BSA-functionalized gold nanoparticles.Scientific reports · 2025Article
- Identifying predictors of surgical site infection in closed patellar fracture surgery: a multicenter study.Scientific reports · 2025Article
- A comparative study of the injury patterns and inflammatory response between suicidal and unintentional falls from height in Germany.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- The importance of systemic inflammatory response measurements as pretransplant risk factors for outcome after allogeneic haematopoietic cell transplantation.British journal of haematology · 2025Article
- Retrospective Analysis of Surgical Site Infection After Titanium Plate Removal Following Orthognathic Surgery.Journal of clinical medicine · 2025Article
- Hip and Knee Arthroplasty Patient Perceptions of Nutrition in the Perioperative Episode of Care.Arthroplasty today · 2025Article
- Risk factors and risk prediction model for mucocutaneous separation in enterostomy patients: A single center experience.World journal of clinical cases · 2024Article
- Improved outcomes with perioperative dietitian-led interventions in patients undergoing total joint arthroplasty: A systematic review.Journal of orthopaedics · 2024Review
- Developing a nomogram for predicting acute complicated course in pediatric acute hematogenous osteomyelitis.Italian journal of pediatrics · 2024Article
- Review
- Wound complication risk factors following open reduction and internal fixation of ankle fractures.International wound journal · 2024Article
- Observational
- Which Pre-Operative, Modifiable Risk Factors are Most Predictive of Complications in orthopedic Upper Extremity Surgery?The archives of bone and joint surgery · 2024Article
- Accuracy of Albumin, Globulin, and Albumin-Globulin Ratio for Diagnosing Periprosthetic Joint Infection: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Review
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroudSurigical site infection has been a challenge for surgeons for many years, the prevalence of serum albumin <3.5g/dL has been reported to be associated with increased orthopaedic complications. However, the prognostic implications and significance of serum albumin <3.5g/dL after orthopaedic surgeries remain ambiguity. In this study, we performed a meta-analysis to access the predictive value of serum albumin level on SSI.
methodsA basic data search was performed in PubMed and Web of Science, in addition, references were manually searched. All of the observational studies contained preoperative albumin, outcomes of SSI or valuable data that could be abstracted and analysed for meta-analysis in orthopaedics. All of the studies were assessed using the classic Newcastle Ottawa Scale (NOS). They conformed to critical quality evaluation standards, and the final data analysis was performed with RevMan 5.2 software.
resultsA total of 112,183 patients included in 13 studies were involved. The pooled MD of albumin between the infection group and the non-infection group was MD = -2.28 (95 % CI -3.97-0.58), which was statistically significant (z = 2.63, P = 0.008). The pooled RR of infection when comparing albumin <3.5 with albumin >3.5 was 2.39 (95 % CI 1.57 3.64), which was statistically significant (z = 4.06, P < 0.0001). Heterogeneity were found in the pooled MD of albumin and in the pooled RR for infection (P = 0.05, I
conclusionOur meta-analysis demonstrated that an albumin level <3.5 g/dL had an almost 2.5 fold increased risk of SSI in orthopaedics, although this conclusion requires well-designed prospective cohort studies to be confirmed further.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.