ArticleInfectious diseases of poverty2017
Genetic source tracking of an anthrax outbreak in Shaanxi province, China.
Article in Infectious diseases of poverty, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 13 citations in OpenAlex.
- Epidemiological Investigation and Source Tracing of an Inhalation Anthrax Case with Traceability to Yunnan Province - Guangdong Province, China, March 2026.China CDC weekly · 2026Article
- Development of Nanopore amplicon sequencing method for culture-free genotyping ofFrontiers in microbiology · 2026Article
- Article
- Rational corticosteroids administration and antibiotic treatment is key to managing cutaneous anthrax.BMC infectious diseases · 2024Article
- Identification and characterization of two Bacillus anthracis bacteriophages.Archives of virology · 2024Article
- Epidemiological Characteristics of Human Anthrax - China, 2018-2021.China CDC weekly · 2022Article
- Genetic diversity of Bacillus anthracis Ames lineage strains in China.BMC infectious diseases · 2020Article
- Epidemiological Investigation and Etiological Analysis of a Cutaneous Anthrax Epidemic Caused by Butchering Sick Cattle in Guizhou, China.Frontiers in public health · 2020Article
- Genetic characteristics of Bacillus anthracis isolated from northwestern China from 1990 to 2016.PLoS neglected tropical diseases · 2018Article
- Sporadic human cutaneous anthrax outbreak in Shaanxi Province, China: report of two cases from 2018.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesArticle
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24 authors at 7 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAnthrax is an acute zoonotic infectious disease caused by the bacterium known as Bacillus anthracis. From 26 July to 8 August 2015, an outbreak with 20 suspected cutaneous anthrax cases was reported in Ganquan County, Shaanxi province in China. The genetic source tracking analysis of the anthrax outbreak was performed by molecular epidemiological methods in this study.
methodsThree molecular typing methods, namely canonical single nucleotide polymorphisms (canSNP), multiple-locus variable-number tandem repeat analysis (MLVA), and single nucleotide repeat (SNR) analysis, were used to investigate the possible source of transmission and identify the genetic relationship among the strains isolated from human cases and diseased animals during the outbreak.
resultsFive strains isolated from diseased mules were clustered together with patients' isolates using canSNP typing and MLVA. The causative B. anthracis lineages in this outbreak belonged to the A.Br.001/002 canSNP subgroup and the MLVA15-31 genotype (the 31 genotype in MLVA15 scheme). Because nine isolates from another four provinces in China were clustered together with outbreak-related strains by the canSNP (A.Br.001/002 subgroup) and MLVA15 method (MLVA15-31 genotype), still another SNR analysis (CL10, CL12, CL33, and CL35) was used to source track the outbreak, and the results suggesting that these patients in the anthrax outbreak were probably infected by the same pathogen clone.
conclusionsIt was deduced that the anthrax outbreak occurred in Shaanxi province, China in 2015 was a local occurrence.
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