Evidence map›Paper›PMID 28092360›Full record

ArticleNature chemical biology2017

Chemical proteomics reveals ADP-ribosylation of small GTPases during oxidative stress.

Nathan P Westcott, Joseph P Fernandez, Henrik Molina, Howard C Hang

Abstract read
In one paragraph

Article in Nature chemical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Poly-ADP-ribosylation dynamics, signaling, and analysis.Environmental and molecular mutagenesis · 2024
    Review
  3. Article
  4. Review
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  7. Profiling of the ADP-Ribosylome in Living Cells.Angewandte Chemie (International ed. in English) · 2022
    Article
  8. Review
  9. Research Progress on Mono-ADP-Ribosyltransferases in Human Cell Biology.Frontiers in cell and developmental biology · 2022
    Review
  10. Article
  11. Review
  12. Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nathan P WestcottLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York, USA.
Joseph P FernandezProteomics Resource Center, The Rockefeller University, New York, New York, USA.
Henrik MolinaProteomics Resource Center, The Rockefeller University, New York, New York, USA.
Howard C HangLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York, USA.
Rockefeller University · US

Funding

Studies on Protein LipidationR01GM087544 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI HANG, HOWARD C · 2010 to 2023
$4.4M
NIGMS NIH HHS R01 GM087544
6 · The paper itself

Abstract

ADP-ribosylation is a post-translational modification that is known to be involved in cellular homeostasis and stress but has been challenging to analyze biochemically. To facilitate the detection of ADP-ribosylated proteins, we show that an alkyne-adenosine analog, N

Indexed as

Oxidative StressProteomicsAdenosine DiphosphateCells, CulturedHEK293 CellsHumansMolecular StructureMonomeric GTP-Binding ProteinsAdenosine DiphosphateMonomeric GTP-Binding Proteins

Identifiers

PMID28092360
PMCPMC5310985
OpenAlexW2575865178

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.