Evidence map›Paper›PMID 28090807›Full record

ArticleThe world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry2018

Neurocognitive function in paediatric obsessive-compulsive disorder.

Daniel A Geller, Amitai Abramovitch, Andrew Mittelman, Abigail Stark, Kesley Ramsey, Allison Cooperman, Lee Baer, S Evelyn Stewart

Abstract read
In one paragraph

Article in The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Neurochemical properties measured byJournal of neural transmission (Vienna, Austria : 1996) · 2021
    Article
  13. Neurocognitive endophenotypes in pediatric OCD probands, their unaffected parents and siblings.Progress in neuro-psychopharmacology & biological psychiatry · 2021
    Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel A Gellera Department of Psychiatry Massachusetts General Hospital & Harvard Medical School , Boston, MA , USA.
Amitai Abramovitcha Department of Psychiatry Massachusetts General Hospital & Harvard Medical School , Boston, MA , USA.ORCID 0000-0001-9640-0970
Andrew Mittelmana Department of Psychiatry Massachusetts General Hospital & Harvard Medical School , Boston, MA , USA.
Abigail Starka Department of Psychiatry Massachusetts General Hospital & Harvard Medical School , Boston, MA , USA.
Kesley Ramseya Department of Psychiatry Massachusetts General Hospital & Harvard Medical School , Boston, MA , USA.
Allison Coopermana Department of Psychiatry Massachusetts General Hospital & Harvard Medical School , Boston, MA , USA.
Lee Baera Department of Psychiatry Massachusetts General Hospital & Harvard Medical School , Boston, MA , USA.
S Evelyn Stewartc Department of Psychiatry , University of British Columbia, BC Children's Hospital , Vancouver , BC , Canada.

Funding

JUVENILE ONSET OCD AS A MEANINGFUL DEVELOPMENT SUBTYPEK08MH001481 · NIMH · MC LEAN HOSPITAL (BELMONT, MA) · PI GELLER, DANIEL A · 1999 to 2003
$676k
NIMH NIH HHS K08 MH001481
6 · The paper itself

Abstract

objectivesThe small body of neuropsychological research in paediatric obsessive-compulsive disorder (OCD) yields inconsistent results. A recent meta-analysis found small effect sizes, concluding that paediatric OCD may not be associated with cognitive impairments, stressing the need for more research. We investigated neuropsychological performance in a large sample of youths with OCD, while assessing potential moderators.

methodsParticipants with OCD (n = 102) and matched controls (n = 161) were thoroughly screened and blindly evaluated for comorbidities, and completed a neuropsychological battery assessing processing speed, visuospatial abilities (VSA), working memory (WM), non-verbal memory (NVM), and executive functions (EF).

resultsCompared to controls, youths with OCD exhibited underperformance on tasks assessing processing speed. On tests of VSA and WM, underperformance was found only on timed tasks. There were no differences on NVM and EF tasks. Notably, the OCD group's standardised scores were in the normative range. Test performance was not associated with demographic or clinical variables.

conclusionsYouths with OCD exhibited intact performance on memory and EF tests, but slower processing speed, and underperformance only on timed VSA and WM tasks. While the OCD group performed in the normative range, these findings reveal relative weaknesses that may be overlooked. Such an oversight may be of particular importance in clinical and school settings.

Indexed as

AdolescentChildCognitive DysfunctionExecutive FunctionFemaleHumansMaleObsessive-Compulsive DisorderPsychomotor Performancechildrencomorbidityexecutive functionsNeuropsychological testsprocessing speed

Identifiers

PMID28090807
PMCPMC5555842

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.