Evidence map›Paper›PMID 28090641›Full record

ArticleClinical and experimental immunology2017

In-vivo quantitative assessment of the therapeutic response in a mouse model of collagen-induced arthritis using

A Mitra, S Kundu-Raychaudhuri, C Abria, A Rona, A J Chaudhari, S P Raychaudhuri

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and experimental immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Multimodal [Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

A MitraDivision of Dermatology, University of California Davis, School of Medicine, Sacramento, CA, USA.ORCID 0000-0003-2385-7325
S Kundu-RaychaudhuriVeterans Affairs Medical Center, Mather, CA, USA.
C AbriaVeterans Affairs Medical Center, Mather, CA, USA.
A RonaVeterans Affairs Medical Center, Mather, CA, USA.
A J ChaudhariDepartment of Radiology, University of California Davis, School of Medicine, Sacramento, CA, USA.
S P RaychaudhuriVeterans Affairs Medical Center, Mather, CA, USA.
Veterans Health Administration · USUniversity of California, Davis · US

Funding

UC DAVIS CLINICAL AND TRANSLATIONAL SCIENCE CENTER: BPCAUL1RR024146 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERGLUND, LARS F · 2006 to 2011
$27.0M
Building Interdisciplinary Research Careers in Womens Health at UC Davis - Administrative SupplementK12HD051958 · NICHD · UNIVERSITY OF CALIFORNIA DAVIS · PI LANE, NANCY E · 2005 to 2023
$9.6M
Quasi-rigid image registration for DCE-MRIR03EB015099 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHAUDHARI, ABHIJIT J · 2013 to 2014
$143k
NCRR NIH HHS UL1 RR024146NIBIB NIH HHS R03 EB015099NICHD NIH HHS K12 HD051958
6 · The paper itself

Abstract

Mouse collagen-induced arthritis (CIA) is the most commonly used animal model to investigate underlying pathogenesis of autoimmune arthritis and to demonstrate the therapeutic efficacy of novel drugs in autoimmune arthritis. The conventional read-outs of CIA are clinical score and histopathology, which have several limitations, including (i) subjected to observer bias; and (ii) longitudinal therapeutic efficacy of a new drug cannot be determined. Thus, a robust, non-invasive, in-vivo drug screening tool is currently an unmet need. Here we have assessed the utility of

Indexed as

AnimalsAnti-Inflammatory AgentsArthritis, ExperimentalCollagenDisease Models, AnimalDisease ProgressionDrug Evaluation, PreclinicalFluorodeoxyglucose F18JointsLongitudinal StudiesMaleMiceMice, Inbred DBAPositron-Emission TomographyRadiopharmaceuticalsTumor Necrosis Factor-alphaAnti-Inflammatory AgentsCollagenFluorodeoxyglucose F18RadiopharmaceuticalsTumor Necrosis Factor-alphaanti-TNFCIAinflammationPET

Identifiers

PMID28090641
PMCPMC5383438
OpenAlexW2574515856

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.