Evidence map›Paper›PMID 28090331›Full record

ArticleBMJ open respiratory research2016

Prevalence of gastrointestinal dysmotility and complications detected by abdominal plain films after lung transplantation: a single-centre cohort study.

Henriette Heinrich, Anne Neuenschwander, Stefan Russmann, Benjamin Misselwitz, Christian Benden, Macé M Schuurmans

Open access · goldAbstract read
In one paragraph

Article in BMJ open respiratory research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Caecal bascule following lung transplantation.Indian journal of thoracic and cardiovascular surgery · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Henriette HeinrichDivision of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Switzerland.
Anne NeuenschwanderDivision of Pulmonary Medicine , University Hospital Zurich , Zurich , Switzerland.
Stefan RussmannDivision of Clinical Pharmacology and Toxicology , University Hospital Zurich , Zurich , Switzerland.
Benjamin MisselwitzDivision of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Switzerland.
Christian BendenDivision of Pulmonary Medicine , University Hospital Zurich , Zurich , Switzerland.
Macé M SchuurmansDivision of Pulmonary Medicine , University Hospital Zurich , Zurich , Switzerland.ORCID 0000-0001-5404-7566
University Hospital of Zurich · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION AND

aimsGastrointestinal (GI) complications such as gastric retention (GR) and constipation are common after lung transplantation (LT). Abdominal plain films (APFs) are a low-cost diagnostic tool to detect impaired GI function. The goal of our study was to assess the prevalence of GI pathology seen on APF in lung transplant recipients (LTRs) and to identify associated risk factors.

methodsRetrospective analysis of consecutive LTRs followed up between 2001 and 2013. Demographic, radiographic and clinical data were assessed.

results198 patients were included in the study, 166 thereof had more than 1 APF with a mean number of 5 APFs per patient. 163 patients had a detectable radiographic pathology on APF. The proportion of LTR with GR was highest among cystic fibrosis patients (48.5%). Multivariate regression analysis showed a significant association of diabetes with GR with a trend for age and use of opiates as risk factors. Similarly, female sex, advanced age and diabetes showed a trend to be associated with lower GI tract complications. Almost all patients had suffered from at least 1 episode of lower GI dysmotility during a median follow-up of 5.7 years. No clear correlation between GI events and the development of chronic lung allograft dysfunction could be identified.

conclusionsWe found a statistically significant association of diabetes with GR and a progressive increase in the prevalence of GR over time after LT. Lower GI complications affected >80% of LTR and increased over time. Future studies correlating GI transit with APF findings are needed.

Indexed as

Alpha1 Antitrypsin DeficiencyCystic FibrosisImmunodeficiencyLung Transplantation

Identifiers

PMID28090331
PMCPMC5223726
OpenAlexW2566869298

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.