Evidence map›Paper›PMID 28090318›Full record

ArticleClinical & translational immunology2016

Dengue virus antibodies enhance Zika virus infection.

Lauren M Paul, Eric R Carlin, Meagan M Jenkins, Amanda L Tan, Carolyn M Barcellona, Cindo O Nicholson, Scott F Michael, Sharon Isern

Open access · goldAbstract read
In one paragraph

Article in Clinical & translational immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 142 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
142citing papers in PubMed, 1 pooled it
39.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

142 citing papers in PubMed, 1 synthesis or guideline pooled it, 197 citations in OpenAlex.

  1. Pooled it
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  16. Zika Virus Neuropathogenesis-Research and Understanding.Pathogens (Basel, Switzerland) · 2024
    Review
  17. Review
  18. Article
  19. Article
  20. Article

82 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lauren M PaulDepartment of Biological Sciences, College of Arts and Sciences, Florida Gulf Coast University , Fort Myers, FL, USA.
Eric R CarlinDepartment of Biological Sciences, College of Arts and Sciences, Florida Gulf Coast University , Fort Myers, FL, USA.
Meagan M JenkinsDepartment of Biological Sciences, College of Arts and Sciences, Florida Gulf Coast University , Fort Myers, FL, USA.
Amanda L TanDepartment of Biological Sciences, College of Arts and Sciences, Florida Gulf Coast University , Fort Myers, FL, USA.
Carolyn M BarcellonaDepartment of Biological Sciences, College of Arts and Sciences, Florida Gulf Coast University , Fort Myers, FL, USA.
Cindo O NicholsonDepartment of Biological Sciences, College of Arts and Sciences, Florida Gulf Coast University , Fort Myers, FL, USA.
Scott F MichaelDepartment of Biological Sciences, College of Arts and Sciences, Florida Gulf Coast University , Fort Myers, FL, USA.
Sharon IsernDepartment of Biological Sciences, College of Arts and Sciences, Florida Gulf Coast University , Fort Myers, FL, USA.
Florida Gulf Coast University · US

Funding

Design of a human monoclonal antibody-informed dengue vaccineR01AI099210 · NIAID · FLORIDA GULF COAST UNIVERSITY · PI ISERN, SHARON · 2013 to 2016
$1.7M
NIAID NIH HHS R01 AI099210
6 · The paper itself

Abstract

For decades, human infections with Zika virus (ZIKV), a mosquito-transmitted flavivirus, were sporadic, associated with mild disease, and went underreported since symptoms were similar to other acute febrile diseases. Recent reports of severe disease associated with ZIKV have greatly heightened awareness. It is anticipated that ZIKV will continue to spread in the Americas and globally where competent

Identifiers

PMID28090318
PMCPMC5192063
OpenAlexW2951710076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.