Evidence map›Paper›PMID 28090289›Full record

ArticlePulmonary circulation2016

An international physician survey of chronic thromboembolic pulmonary hypertension management.

Henning Gall, Ioana R Preston, Barbara Hinzmann, Sabina Heinz, David Jenkins, Nick H Kim, Irene Lang

Open access · bronzeAbstract read
In one paragraph

Article in Pulmonary circulation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Chronic thromboembolic pulmonary hypertension: anticoagulation and beyond.Hematology. American Society of Hematology. Education Program · 2021
    Article
  10. The evolving role of interventional cardiology in the treatment of pulmonary hypertension.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2021
    Review
  11. Review
  12. Does combination therapy work in chronic thromboembolic pulmonary hypertension?International journal of cardiology. Heart & vasculature · 2020
    Article
  13. Review
  14. Article
  15. The changing landscape of chronic thromboembolic pulmonary hypertension management.European respiratory review : an official journal of the European Respiratory Society · 2017
    Review
  16. An epidemiological analysis of the burden of chronic thromboembolic pulmonary hypertension in the USA, Europe and Japan.European respiratory review : an official journal of the European Respiratory Society · 2017
    Review
  17. Bridging the science into practice.Pulmonary circulation · 2016
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 4 countries.

Henning GallUniversity of Giessen and Marburg Lung Center (UGMLC), Giessen, member of the German Center of Lung Research (DZL), Giessen, Germany.
Ioana R PrestonPulmonary Critical Care and Sleep Division, Tufts Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA.
Barbara HinzmannGlobal Market Research, Bayer Pharma, Berlin, Germany.
Sabina HeinzIpsos Healthcare, London, United Kingdom.
David JenkinsNational Pulmonary Endarterectomy Service, Department of Cardiothoracic Surgery, Papworth Hospital, Cambridge, United Kingdom.
Nick H KimDivision of Pulmonary and Critical Care Medicine, University of California, San Diego, La Jolla, California, USA.
Irene LangAllgemeines Krankenhaus der Stadt Wien, Vienna, Austria.
Bayer (Germany) · DEIpsos (United Kingdom) · GBPapworth Hospital · GBTufts University · USUniversities of Giessen and Marburg Lung Center · DEUniversity of California System · USVienna General Hospital · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted an international study to evaluate practices in the diagnosis and management of patients with chronic thromboembolic pulmonary hypertension (CTEPH) globally across different regions. Between August and October 2012, CTEPH-treating physicians completed a 15-minute online questionnaire and provided patient record data for their 2-5 most recent patients with CTEPH. Overall, 496 physicians (Europe: 260; United States: 152; Argentina: 52; Japan: 32) completed the questionnaire and provided patient record data for 1,748 patients. The proportion of physicians who described themselves as working in or affiliated with a specialized pulmonary hypertension (PH) center ranged from 38% in France and Italy to 83% in the United States. A large proportion of patients did not undergo ventilation/perfusion scanning (46%-67%) or right heart catheterization (24%-57%) for the diagnosis of CTEPH. Referral rates for pulmonary endarterectomy evaluation ranged from 25% in Japan to 44% in Europe, with higher referral rates in PH centers; the main reasons for lack of referral were that surgery was not considered unless medical treatment was failing and patient refusal. Other variations in management included greater use of phosphodiesterase 5 inhibitors in the United States than in Europe and Japan and greater use of combination treatment in the United States than in Europe. Physicians' perceptions of their treatment strategy were generally consistent with patient record data. Results from this study, which includes a global aspect of CTEPH care, demonstrate not only regional differences in CTEPH management but, more importantly, considerable nonadherence to the diagnosis and treatment guidelines for CTEPH, even in PH centers.

Indexed as

chronic thromboembolic pulmonary hypertensionclinical practicediagnosisguidelinespulmonary arterial hypertension–specific therapies

Identifiers

PMID28090289
PMCPMC5210056
OpenAlexW2468329702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.