Evidence map›Paper›PMID 28089871›Full record

Observational studyThe Journal of allergy and clinical immunology2017

Parents' childhood socioeconomic circumstances are associated with their children's asthma outcomes.

Edith Chen, Madeleine U Shalowitz, Rachel E Story, Katherine B Ehrlich, Erika M Manczak, Paula J Ham, Van Le, Gregory E Miller

Open access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in The Journal of allergy and clinical immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Edith ChenDepartment of Psychology, Institute for Policy Research, Northwestern University, Evanston, Ill. Electronic address: edith.chen@northwestern.edu.
Madeleine U ShalowitzNorthShore University Health Systems, Evanston, Ill.
Rachel E StoryNorthShore University Health Systems, Evanston, Ill.
Katherine B EhrlichDepartment of Psychology, Institute for Policy Research, Northwestern University, Evanston, Ill.
Erika M ManczakDepartment of Psychology, Institute for Policy Research, Northwestern University, Evanston, Ill.
Paula J HamDepartment of Psychology, Institute for Policy Research, Northwestern University, Evanston, Ill.
Van LeDepartment of Psychology, Institute for Policy Research, Northwestern University, Evanston, Ill.
Gregory E MillerDepartment of Psychology, Institute for Policy Research, Northwestern University, Evanston, Ill.
Northwestern University · USNorthShore University HealthSystem · US

Funding

Multi-Level Understanding of Social Contributors to SES Disparities in AsthmaR01HL108723 · NHLBI · NORTHWESTERN UNIVERSITY · PI CHEN, EDITH · 2012 to 2016
$2.0M
NHLBI NIH HHS R01 HL108723
6 · The paper itself

Abstract

backgroundPrevious literature documents associations between low socioeconomic status (SES) and poor health outcomes, including asthma. However, this literature has largely focused on the effects of current family circumstances.

objectiveWe sought to test an intergenerational hypothesis, that the childhood SES that parents experience will be associated with asthma outcomes in their children, independent of effects of current family SES. Second, we aimed to test whether this association is in part due to difficulties in current parent-child relationships.

methodsThis was an observational study, whereby 150 parents were interviewed about their childhood SES and their children (physician-diagnosed asthma, ages 9-17 years) were interviewed about current family stress. Asthma control was assessed by parent report and child report (primary outcome), and blood was collected from children to measure cytokine production relevant to asthma (secondary outcomes).

resultsTo the degree that parents had lower childhood SES, their offspring showed worse asthma outcomes across multiple indicators. This included lower asthma control scores (parent and child report, Ps < .05), and greater stimulated production of T

conclusionsThese results suggest the potential "long reach" of low SES across generations, and the importance of expanding theories of how the social environment can affect childhood asthma to include characteristics of earlier generations.

Indexed as

Parent-Child RelationsSocial EnvironmentAdolescentAsthmaChildCytokinesFemaleHumansLeukocytes, MononuclearMaleParentsSocioeconomic FactorsStress, PsychologicalSurveys and QuestionnairesCytokinesasthmachildhoodfamily stressSocioeconomic status

Identifiers

PMID28089871
PMCPMC5509526
OpenAlexW2577081227

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.