Evidence map›Paper›PMID 28089452›Full record

ArticleStructure (London, England : 1993)2017

Co-Folding of a FliF-FliG Split Domain Forms the Basis of the MS:C Ring Interface within the Bacterial Flagellar Motor.

Michael J Lynch, Robert Levenson, Eun A Kim, Ria Sircar, David F Blair, Frederick W Dahlquist, Brian R Crane

Abstract read
In one paragraph

Article in Structure (London, England : 1993), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. The ancient E-ring in bacterial flagellar motors.FEMS microbiology reviews · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Molecular model of a bacterial flagellar motorbioRxiv : the preprint server for biology · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Control of the flagellation pattern inJournal of bacteriology · 2023
    Article
  16. Article
  17. Flagellar motor remodeling during swarming requires FliL.bioRxiv : the preprint server for biology · 2023
    Article
  18. Article
  19. Ring formation byBiophysics and physicobiology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Michael J LynchDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.
Robert LevensonDepartment of Chemistry and Biochemistry, University of California Santa Barbara, Santa Barbara, CA 93106-9510, USA.
Eun A KimDepartment of Biology, University of Utah, Salt Lake City, UT 84112, USA.
Ria SircarDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.
David F BlairDepartment of Biology, University of Utah, Salt Lake City, UT 84112, USA.
Frederick W DahlquistDepartment of Chemistry and Biochemistry, University of California Santa Barbara, Santa Barbara, CA 93106-9510, USA.
Brian R CraneDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA. Electronic address: bc69@cornell.edu.

Funding

Overall (pp. 40-62)P41GM103485 · NIGMS · CORNELL UNIVERSITY · PI CERIONE, RICHARD A. · 2012 to 2018
$15.5M
Overall EvaluationP41GM103403 · NIGMS · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2012 to 2017
$14.3M
Molecular Mechanisms of Signal Transduction Involving Light, Redox and Transmembrane ComplexesR35GM122535 · NIGMS · CORNELL UNIVERSITY · PI BRIAN R CRANE · 2017 to 2026
$7.1M
CHEMISTRY OF BIOLOGICAL SYSTEMST32GM008500 · NIGMS · CORNELL UNIVERSITY ITHACA · PI LIN, HENING · 1996 to 2020
$5.4M
MECHANISTIC STUDIES OF BACTERIAL CHEMOTAXISR01GM059544 · NIGMS · UNIVERSITY OF OREGON · PI DAHLQUIST, FREDERICK W. · 1999 to 2018
$4.8M
Structure and Mechanism of the Flagellar Switch ComplexR01GM064664 · NIGMS · UNIVERSITY OF UTAH · PI BLAIR, DAVID F., CRANE, BRIAN R · 2003 to 2017
$4.1M
NIGMS NIH HHS P41 GM103403NIGMS NIH HHS P41 GM103485NIGMS NIH HHS R01 GM059544NIGMS NIH HHS R01 GM064664NIGMS NIH HHS R35 GM122535NIGMS NIH HHS T32 GM008500
6 · The paper itself

Abstract

The interface between the membrane (MS) and cytoplasmic (C) rings of the bacterial flagellar motor couples torque generation to rotation within the membrane. The structure of the C-terminal helices of the integral membrane protein FliF (FliF

Indexed as

Amino Acid MotifsBacterial ProteinsBinding SitesBiomechanical PhenomenaCell MembraneCloning, MolecularCrystallography, X-RayEscherichia coliFlagellaGene ExpressionMembrane ProteinsModels, MolecularProtein BindingProtein Conformation, alpha-HelicalProtein FoldingProtein Interaction Domains and MotifsBacterial ProteinsFlif protein, BacteriaFlig protein, BacteriaMembrane ProteinsRecombinant Fusion Proteinsassemblychemotaxiscross-linkingdomain shufflingflagellar motormolecular machinemotilityswitch complexX-ray structure

Identifiers

PMID28089452
PMCPMC5387689

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.