Evidence map›Paper›PMID 28089224›Full record

ArticleMedical engineering & physics2017

Loading of the medial meniscus in the ACL deficient knee: A multibody computational study.

Trent M Guess, Swithin Razu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical engineering & physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

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  20. [Effect of HBP-A on meniscal injury and pathological hypertrophy and calcification of the meniscus].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Trent M GuessUniversity of Missouri, Department of Physical Therapy, Department of Orthopaedic Surgery, 801 Clark Hall, Columbia, MO 65211-4250, United States . Electronic address: guesstr@health.missouri.edu.
Swithin RazuUniversity of Missouri, Department of Physical Therapy, Department of Orthopaedic Surgery, 801 Clark Hall, Columbia, MO 65211-4250, United States.
University of Missouri · USUniversity of Missouri Health System · US

Funding

Subject Specific Concurrent Simulation of Movement and Natural Knee Contact MechaR15AR061698 · NIAMS · UNIVERSITY OF MISSOURI KANSAS CITY · PI GUESS, TRENT M. · 2011 to 2011
$446k
NIAMS NIH HHS R15 AR061698
6 · The paper itself

Abstract

The menisci of the knee reduce tibiofemoral contact pressures and aid in knee lubrication and nourishment. Meniscal injury occurs in half of knees sustaining anterior cruciate ligament injury and the vast majority of tears in the medial meniscus transpire in the posterior horn region. In this study, computational multibody models of the knee were derived from medical images and passive leg motion for two female subjects. The models were validated against experimental measures available in the literature and then used to evaluate medial meniscus contact force and internal hoop tension. The models predicted that the loss of anterior cruciate ligament (ACL) constraint increased contact and hoop forces in the medial menisci by a factor of 4 when a 100N anterior tibial force was applied. Contact forces were concentrated in the posterior horn and hoop forces were also greater in this region. No differences were found in contact or hoop tension between the intact and ACL deficient (ACLd) knees when only a 5Nm external tibial torque was applied about the long axis of the tibia. Combining a 100N anterior tibial force and a 5Nm external tibial torque increased posterior horn contact and hoop forces, even in the intact knee. The results of this study show that the posterior horn region of the medial meniscus experiences higher contact forces and hoop tension, making this region more susceptible to injury, especially with the loss of anterior tibia motion constraint provided by the ACL. The contribution of the dMCL in constraining posterior medial meniscus motion, at the cost of higher posterior horn hoop tension, is also demonstrated.

Indexed as

Anterior Cruciate LigamentComputer SimulationAdultBiomechanical PhenomenaFemaleFemurHumansMenisci, TibialModels, BiologicalMovementTibiaWeight-BearingYoung AdultAnterior cruciate ligamentComputational biomechanicsMedial collateral ligamentMedial meniscusMenisci

Identifiers

PMID28089224
PMCPMC5316296
OpenAlexW2576517066

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.