Evidence map›Paper›PMID 28088880›Full record

ReviewTherapeutic delivery2017

Recent advances in light-responsive on-demand drug-delivery systems.

Chase S Linsley, Benjamin M Wu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Therapeutic delivery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Hypothalamic wars: the last nanodelivery.Reviews in endocrine & metabolic disorders · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Nanocarriers for cutting-edge cancer immunotherapies.Journal of translational medicine · 2025
    Review
  18. Review
  19. Review
  20. Review

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chase S LinsleyDepartment of Bioengineering, University of California, Los Angeles, CA 90095, USA.
Benjamin M WuDepartment of Bioengineering, University of California, Los Angeles, CA 90095, USA.

Funding

Growth factor delivery using light-sensitive fibrin to treat chronic woundsR21AR064437 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TAWIL, BILL, WU, BENJAMIN M · 2014 to 2015
$359k
NIAMS NIH HHS R21 AR064437
6 · The paper itself

Abstract

The convergence of wearable sensors and personalized medicine enhance the ability to sense and control the drug composition and dosage, as well as location and timing of administration. To date, numerous stimuli-triggered smart drug-delivery systems have been developed to detect changes in light, pH, temperature, biomolecules, electric field, magnetic field, ultrasound and mechanical forces. This review examines the major advances within the last 5 years for the three most common light-responsive drug delivery-on-demand strategies: photochemical, photoisomerization and photothermal. Examples are highlighted to illustrate progress of each strategy in drug delivery applications, and key limitations are identified to motivate future research to advance this important field.

Indexed as

Drug Delivery SystemsLightPharmaceutical PreparationsPharmaceutical Preparationscontrolled releasedrug deliverylightlight-responsive drug deliverypersonalized medicinephotochemically triggered releasephotocleavablephotoisomerizationphotothermal releasesmart drug-delivery system

Identifiers

PMID28088880
PMCPMC5561969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.