Evidence map›Paper›PMID 28088841›Full record

ArticleMicrobiologyOpen2017

Intracellular fate of Ureaplasma parvum entrapped by host cellular autophagy.

Fumiko Nishiumi, Michinaga Ogawa, Yukiko Nakura, Yusuke Hamada, Masahiro Nakayama, Jiro Mitobe, Atsushi Hiraide, Norio Sakai, Makoto Takeuchi, Tamotsu Yoshimori and 1 more

Open access · goldAbstract read
In one paragraph

Article in MicrobiologyOpen, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Host immune dysfunction and Mycoplasma pneumoniae immune evasion: dual drivers of pathogenesis in Mycoplasma pneumoniae pneumonia.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
  2. Article
  3. AntenatalInternational journal of molecular sciences · 2024
    Article
  4. Article
  5. Unveiling the stealthy tactics: mycoplasma's immune evasion strategies.Frontiers in cellular and infection microbiology · 2023
    Review
  6. Article
  7. Exosomes fromFrontiers in cell and developmental biology · 2022
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Frontiers in cellular and infection microbiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Fumiko NishiumiDepartment of Developmental Medicine, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan.
Michinaga OgawaDepartment of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan.
Yukiko NakuraDepartment of Developmental Medicine, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan.
Yusuke HamadaDepartment of Pediatrics, Osaka University Graduate School of Medicine, Osaka, Japan.
Masahiro NakayamaDepartment of Pathology, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan.
Jiro MitobeDepartment of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan.
Atsushi HiraideCritical Care Medical Center, Faculty of Medicine, Kindai University, Osaka, Japan.
Norio SakaiDepartment of Pediatrics, Osaka University Graduate School of Medicine, Osaka, Japan.
Makoto TakeuchiDepartment of Pathology, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan.
Tamotsu YoshimoriDepartment of Genetics, Graduate School of Medicine, Osaka University, Osaka, Japan.
Itaru YanagiharaDepartment of Developmental Medicine, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan.
Osaka Medical Center for Cancer and Cardiovascular Diseases · JPOsaka University · JPNational Institute of Infectious Diseases · JPKindai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genital mycoplasmas, including Ureaplasma spp., are among the smallest human pathogenic bacteria and are associated with preterm birth. Electron microscopic observation of U. parvum showed that these prokaryotes have a regular, spherical shape with a mean diameter of 146 nm. U. parvum was internalized into HeLa cells by clathrin-mediated endocytosis and survived for at least 14 days around the perinuclear region. Intracellular U. parvum reached endosomes in HeLa cells labeled with EEA1, Rab7, and LAMP-1 within 1 to 3 hr. After 3 hr of infection, U. parvum induced the cytosolic accumulation of galectin-3 and was subsequently entrapped by the autophagy marker LC3. However, when using atg7

Indexed as

AutophagyHost-Pathogen InteractionsAutophagosomesEpithelial CellsHeLa CellsHumansImmune EvasionMicroscopy, ElectronUreaplasmaautophagyendocytosisexosomegalectinUreaplasma spp

Identifiers

PMID28088841
PMCPMC5458467
OpenAlexW2579226561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.