ArticleAmerican journal of ophthalmology2017
Relationship Between Central Retinal Vessel Trunk Location and Visual Field Loss in Glaucoma.
Article in American journal of ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Movement of central retinal vessel trunk and its correlation with lamina cribrosa pores movement after short-term intraocular pressure elevation.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Changes in Major Retinal Blood Vessel Position Outside the Optic Nerve Head in Glaucomatous Eyes.Journal of ophthalmic & vision research · 2025Article
- Features Associated with Visible Lamina Cribrosa Pores in Individuals of African Ancestry with Glaucoma: Primary Open-Angle African Ancestry Glaucoma Genetics (POAAGG) Study.Vision (Basel, Switzerland) · 2024Article
- Association of macular vessel density and ganglion cell complex thickness with central visual field progression in glaucoma.The British journal of ophthalmology · 2023Article
- Optic Disc Morphology and Paracentral Scotoma in Patients with Open-Angle Glaucoma and Myopia.Journal of clinical medicine · 2023Article
- The Relationship Between Optic Disc and Retinal Artery Position and Glaucomatous Visual Field Progression.Investigative ophthalmology & visual science · 2021Article
- The Effect of Ametropia on Glaucomatous Visual Field Loss.Journal of clinical medicine · 2021Article
- Article
- Nasalization of Central Retinal Vessel Trunk Predicts Rapid Progression of Central Visual Field in Open-Angle Glaucoma.Scientific reports · 2020Article
- Baseline 24-2 Central Visual Field Damage Is Predictive of Global Progressive Field Loss.American journal of ophthalmology · 2018Article
- Article
- The Interrelationship between Refractive Error, Blood Vessel Anatomy, and Glaucomatous Visual Field Loss.Translational vision science & technology · 2018Article
- Ametropia, retinal anatomy, and OCT abnormality patterns in glaucoma. 2. Impacts of optic nerve head parameters.Journal of biomedical optics · 2017Article
- Location of the Central Retinal Vessel Trunk in the Laminar and Prelaminar Tissue of Healthy and Glaucomatous Eyes.Scientific reports · 2017Article
- Associations between Optic Nerve Head-Related Anatomical Parameters and Refractive Error over the Full Range of Glaucoma Severity.Translational vision science & technology · 2017Article
- Detection of central visual field defects in early glaucomatous eyes: Comparison of Humphrey and Octopus perimetry.PloS one · 2017Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
Abstract
purposeTo study the relationship between horizontal central retinal vessel trunk location (CRVTL) on glaucomatous optic discs and sector-specific visual field (VF) loss.
designRetrospective cross-sectional study.
methodsCRVTL of 421 eyes from 421 patients was manually tracked on the horizontal optic disc axis on fundus images. Focal circumpapillary retinal nerve fiber layer thickness (cpRNFLT) measurements were extracted from optical coherence tomography (OCT). The relationship between focal visual field (VF) loss and CRVTL and focal cpRNFLT was studied by linear regression models. Furthermore, we related central VF loss to CRVTL and focal cpRNFLT separately for mild (VF mean deviation [MD] ≥-6 dB), moderate (-12 dB ≤ MD <-6 dB), and severe (MD <-12 dB) glaucoma.
resultsCRVTL nasalization was significantly correlated only to central VF loss (Garway-Heath scheme [central 6 locations, C6]: correlation: r = -0.16, P < .001; macular vulnerability zone [central 2 locations, C2]: r = -0.14, P = .003; central 4 locations [C4]: r = -0.17, P < .001). While focal cpRNFLT at the sectors corresponding to C2 and C6 was significantly correlated to the respective VF sectors as well (C2: r = 0.15, P = .002; C6: r = 0.10, P = .03), multivariate models combining cpRNFLT and CRVTL substantially improved structure-function models compared with cpRNFLT alone (likelihood ratio tests, C2 and C6: P < .001). The correlations between CRVTL and central VF loss of C4 were -0.11 (P = .04), -0.39 (P = .01), and -0.63 (P = .002) for mild, moderate, and severe glaucoma, respectively.
conclusionsCRVTL nasalization is significantly and exclusively correlated to central VF loss for all glaucoma severities independent of cpRNFLT, and thus might be a structural biomarker of central VF loss.
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Registered trials
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