Evidence map›Paper›PMID 28087642›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017

STXBP4 Drives Tumor Growth and Is Associated with Poor Prognosis through PDGF Receptor Signaling in Lung Squamous Cell Carcinoma.

Yukihiro Otaka, Susumu Rokudai, Kyoichi Kaira, Michiru Fujieda, Ikuko Horikoshi, Reika Iwakawa-Kawabata, Shinji Yoshiyama, Takehiko Yokobori, Yoichi Ohtaki, Kimihiro Shimizu and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. p63-related signaling at a glance.Journal of cell science · 2020
    Review
  7. Review
  8. Article
  9. Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2019
    Article
  10. Article
  11. STXBP4 regulates APC/C-mediated p63 turnover and drives squamous cell carcinogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Yukihiro Otaka *Department of Molecular Pharmacology and Oncology, Gunma University, Gunma, Japan.
Susumu Rokudai *Department of Molecular Pharmacology and Oncology, Gunma University, Gunma, Japan.
Kyoichi KairaDepartment of Oncology Clinical Development, Gunma University, Gunma, Japan.
Michiru FujiedaDepartment of Molecular Pharmacology and Oncology, Gunma University, Gunma, Japan.
Ikuko HorikoshiDepartment of Molecular Pharmacology and Oncology, Gunma University, Gunma, Japan.
Reika Iwakawa-KawabataDepartment of Molecular Pharmacology and Oncology, Gunma University, Gunma, Japan.
Shinji YoshiyamaDivision of Integrated Oncology Research, Gunma University Initiative for Advanced Research (GIAR), Gunma, Japan.
Takehiko YokoboriDepartment of Molecular Pharmacology and Oncology, Gunma University, Gunma, Japan.
Yoichi OhtakiDepartment of Thoracic Visceral Organ Surgery, Gunma University, Gunma, Japan.
Kimihiro ShimizuDepartment of Thoracic Visceral Organ Surgery, Gunma University, Gunma, Japan.
Tetsunari OyamaDepartment of Pathology, Gunma University, Gunma, Japan.
Jun'ichi TamuraDepartment of General Medicine, Gunma University, Gunma, Japan.
Carol PrivesDepartment of Biological Sciences, Columbia University, NY, USA.
Masahiko NishiyamaDepartment of Molecular Pharmacology and Oncology, Gunma University, Gunma, Japan.
Gunma University · JPColumbia University · US

Funding

Scientific ReagentsP01CA087497 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI PRIVES, CAROL · 2000 to 2021
$35.4M
NCI NIH HHS P01 CA087497
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAged, 80 and overAnimalsCarcinoma, Squamous CellCell Line, TumorCell ProliferationFemaleGene Expression Regulation, NeoplasticHumansLung NeoplasmsMaleMiceMiddle AgedPrognosisReceptor, Platelet-Derived Growth Factor alphaReceptor, Platelet-Derived Growth Factor alphaSTXBP4 protein, humanVesicular Transport Proteins

Identifiers

PMID28087642
PMCPMC5496791
OpenAlexW2578611102

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.