Evidence map›Paper›PMID 28087538›Full record

ArticleBlood2017

BCAP inhibits proliferation and differentiation of myeloid progenitors in the steady state and during demand situations.

Jeffrey M Duggan, Matthew B Buechler, Rebecca M Olson, Tobias M Hohl, Jessica A Hamerman

Open access · bronzeAbstract read
In one paragraph

Article in Blood, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Frontiers in immunology · 2020
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jeffrey M DugganImmunology Program, Benaroya Research Institute, Seattle, WA.
Matthew B BuechlerImmunology Program, Benaroya Research Institute, Seattle, WA.
Rebecca M OlsonDepartment of Immunology, University of Washington, Seattle, WA; and.
Tobias M HohlInfectious Diseases Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Jessica A HamermanImmunology Program, Benaroya Research Institute, Seattle, WA.
Benaroya Research InstituteUniversity of Washington · USMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
INITIATION OF THE IMMUNE RESPONSE TO ASPERGILLUS FUMIGATUSR01AI093808 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI HOHL, TOBIAS M · 2011 to 2020
$4.9M
INITIATION OF THE IMMUNE RESPONSE TO ASPERGILLUS FUMIGATUSR37AI093808 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI TOBIAS M HOHL · 2021 to 2026
$4.2M
BASIC IMMUNOLOGYT32CA009537 · NCI · UNIVERSITY OF WASHINGTON · PI GOVERMAN, JOAN M · 1986 to 2012
$3.1M
Regulation of dendritic cell inflammatory responsesR01AI081948 · NIAID · BENAROYA RESEARCH INST AT VIRGINIA MASON · PI HAMERMAN, JESSICA A · 2010 to 2014
$2.2M
Basic Training at the Intersection of Innate and Adaptive Immunity in DiseaseT32AI106677 · NIAID · UNIVERSITY OF WASHINGTON · PI GALE, MICHAEL, GOVERMAN, JOAN M · 2013 to 2022
$2.1M
BCAP/PI3K regulation of innate immunity to Listeria monocytogenesR01AI113325 · NIAID · BENAROYA RESEARCH INST AT VIRGINIA MASON · PI HAMERMAN, JESSICA A · 2015 to 2019
$2.0M
NCI NIH HHS P30 CA008748NCI NIH HHS T32 CA009537NIAID NIH HHS R01 AI081948NIAID NIH HHS R01 AI113325NIAID NIH HHS R37 AI093808NIAID NIH HHS T32 AI106677
6 · The paper itself

Abstract

B-cell adaptor for phosphatidylinositol 3-kinase (BCAP) is a signaling adaptor expressed in mature hematopoietic cells, including monocytes and neutrophils. Here we investigated the role of BCAP in the homeostasis and development of these myeloid lineages. BCAP

Indexed as

Cell DifferentiationCell ProliferationAdaptor Proteins, Signal TransducingAnimalsCell LineageHomeostasisMiceMonocytesMyeloid Progenitor CellsMyelopoiesisNeutrophilsAdaptor Proteins, Signal TransducingPik3ap1 protein, mouse

Identifiers

PMID28087538
PMCPMC5356451
OpenAlexW2572640259

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.