Evidence map›Paper›PMID 28087467›Full record

ArticlePreventive medicine2017

Positive childhood experiences and ideal cardiovascular health in midlife: Associations and mediators.

Natalie Slopen, Ying Chen, Jennifer L Guida, Michelle A Albert, David R Williams

Abstract read
In one paragraph

Article in Preventive medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Racial Differences in Sleep Outcomes in the First Two Years of College.Journal of racial and ethnic health disparities · 2026
    Article
  5. Review
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  13. Reimagining the Juvenile Justice System Through the Healthy Outcomes from Positive Experiences Framework.International journal of environmental research and public health · 2025
    Article
  14. Positive childhood experiences and adult cardiovascular health.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Article
  15. Positive Childhood Experiences, Cognition, and Biomarkers of Alzheimer's Disease.International journal of environmental research and public health · 2025
    Article
  16. Health Associations of Positive Childhood Experiences: A Scoping Review of the Literature.International journal of environmental research and public health · 2025
    Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Natalie SlopenDepartment of Epidemiology and Biostatistics, University of Maryland, College Park, School of Public Health, United States. Electronic address: nslopen@umd.edu.
Ying ChenDepartment of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, United States.
Jennifer L GuidaDepartment of Epidemiology and Biostatistics, University of Maryland, College Park, School of Public Health, United States.
Michelle A AlbertDivision of Cardiovascular Medicine, Division of Cardiology, Department of Medicine, University of California, San Francisco, United States.
David R WilliamsDepartment of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, United States; Department of African and African American Studies, Harvard University, United States.

Funding

U19 MIDlife in the United States-Diversity Supplement-WellsU19AG051426 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CAROL D. RYFF · 2016 to 2026
$74.8M
STATISTICS COREP01AG020166 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI RYFF, CAROL D. · 2002 to 2015
$50.6M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
Longitudinal Perspectives on Race and Health in MIDUS: Insights from MilwaukeeR01AG047154 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI RYFF, CAROL D. · 2015 to 2017
$1000k
NCATS NIH HHS UL1 TR000427NCRR NIH HHS UL1 RR025011NIA NIH HHS P01 AG020166NIA NIH HHS R01 AG047154NIA NIH HHS U19 AG051426
6 · The paper itself

Abstract

In 2010, the American Heart Association introduced a new conceptual framework to encourage a focus on primary prevention and provided a definition for "ideal cardiovascular health". In this study we examined the relationship between positive childhood experience and ideal cardiovascular health in mid-life, and the extent to which education, depression, and social support mediate this association. Data are from participants in the Midlife and Aging in the United States study who completed a clinic-based assessment of health (N=1255, aged 34-84years, 2004-2005). We created a positive childhood experiences index based on retrospective report of eight childhood experiences, and calculated a continuous ideal cardiovascular health score for each participant following the American Heart Association's definition of ideal, intermediate and poor cardiovascular health across seven health metrics (analyses conducted in 2015-2016). Positive childhood experiences were associated with ideal cardiovascular health: compared to individuals in the lowest quartile, respondents in the second, third, and fourth quartile of positive childhood experiences scored 0.42 (standard error (SE)=0.18), 0.92 (SE=0.18) and 1.04 (SE=0.18) units higher on ideal cardiovascular health, adjusting for age, sex, and race. Respondent's education, depression status, and social support fully mediated the direct effect of positive childhood experiences on ideal cardiovascular health, with the largest indirect effect for education. These results suggest that positive childhood experiences are associated with ideal cardiovascular health in midlife. Strategies to promote cardiovascular wellbeing may benefit from a focus on social interventions early in life; educational attainment, major depression, and social support may represent key points of intervention.

Indexed as

Health StatusAgingCardiovascular DiseasesDepressionEducational StatusFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsSocial SupportSurveys and QuestionnairesUnited StatesAgingChildhood factorsEpidemiologyIdeal cardiovascular healthLife course

Identifiers

PMID28087467
PMCPMC5430499

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.