Evidence map›Paper›PMID 28087266›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2017

Assessment of Sex Differences in Body Composition Among Adolescents With Anorexia Nervosa.

Jason M Nagata, Neville H Golden, Rebecka Peebles, Jin Long, Stuart B Murray, Mary B Leonard, Jennifer L Carlson

Abstract readComparative Study
In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Endocrine complications of anorexia nervosa.Journal of eating disorders · 2023
    Review
  5. Autonomic nervous system function in women with anorexia nervosa.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022
    Article
  6. Review
  7. Article
  8. Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2019
    Article
  9. Article
  10. Article
  11. Differential Risk Factors for Unhealthy Weight Control Behaviors by Sex and Weight Status Among U.S. Adolescents.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2018
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Assessment of Sex Differences in Fracture Risk Among Patients With Anorexia Nervosa: A Population-Based Cohort Study Using The Health Improvement Network.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jason M NagataDepartment of Pediatrics, Stanford University School of Medicine, Palo Alto, California; Department of Pediatrics, Division of Adolescent and Young Adult Medicine, University of California, San Francisco, San Francisco, California. Electronic address: jasonmnagata@gmail.com.
Neville H GoldenDepartment of Pediatrics, Stanford University School of Medicine, Palo Alto, California.
Rebecka PeeblesDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Jin LongDepartment of Pediatrics, Stanford University School of Medicine, Palo Alto, California.
Stuart B MurrayDepartment of Psychiatry, University of California, San Francisco, San Francisco, California.
Mary B LeonardDepartment of Pediatrics, Stanford University School of Medicine, Palo Alto, California.
Jennifer L CarlsonDepartment of Pediatrics, Stanford University School of Medicine, Palo Alto, California.
Stanford University · USUniversity of California, San Francisco · USChildren's Hospital of Philadelphia · US

Funding

Multi-center Randomized Controlled Trial of Refeeding in Anorexia NervosaR01HD082166 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GARBER, ANDREA K · 2015 to 2025
$5.7M
Weight gain and functional body composition in adolescents with anorexia nervosaK23DK100558 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI PEEBLES, REBECKA · 2015 to 2019
$900k
NICHD NIH HHS R01 HD082166NIDDK NIH HHS K23 DK100558
6 · The paper itself

Abstract

purposeTo compare deficits in fat mass (FM) and lean body mass (LM) among male and female adolescents with anorexia nervosa (AN) and to identify other covariates associated with body composition.

methodsWe retrospectively reviewed electronic medical records of all subjects aged 9-20 years with a Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition diagnosis of AN and dual-energy x-ray absorptiometry scans after initial evaluation at Stanford between March 1997 and February 2011. From the dual-energy x-ray absorptiometry scans, LM and FM results were converted to age-, height-, sex-, and race-specific Z-scores for age using the National Health and Nutrition Examination Survey reference data.

resultsA total of 16 boys and 119 girls with AN met eligibility criteria. The FM Z-score in girls with AN (-3.24 ± 1.50) was significantly lower than that in boys with AN (-2.41 ± .96) in unadjusted models (p = .007). LM was reduced in both girls and boys with AN, but there was no significant sex difference in LM Z-scores. In multivariate models, lower percentage median body mass index was significantly associated with lower FM Z-scores (β = .08, p < .0001) and lower LM Z-score (β = .03, p = .0002), whereas lower whole body bone mineral content Z-score was significantly associated with lower LM Z-score (β = .21, p = .0006).

conclusionsFM deficits in girls were significantly greater than those in boys with AN in unadjusted models; however, the degree of malnutrition appeared to be the primary factor accounting for this difference. There were no significant sex differences in FM or LM in adjusted models.

Indexed as

Body CompositionAbsorptiometry, PhotonAdolescentAnorexia NervosaBody Fat DistributionBody Mass IndexCaliforniaChildDiagnostic and Statistical Manual of Mental DisordersElectronic Health RecordsFemaleHumansMaleMalnutritionRetrospective StudiesSex FactorsAnorexia nervosaBody compositionDual-energy x-ray absorptiometryEating disordersFemalesMalesSex differences

Identifiers

PMID28087266
PMCPMC6402565
OpenAlexW2578891526

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.