Evidence map›Paper›PMID 28087224›Full record

ArticleBrain research2017

5-HT

Matthew Brodsky, Adam J Lesiak, Alex Croicu, Nathalie Cohenca, Jane M Sullivan, John F Neumaier

Open access · greenAbstract read
In one paragraph

Article in Brain research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. The nociceptor primary cilium.Brain : a journal of neurology · 2026
    Review
  3. Primary cilia and neural computation.Journal of biomedical science · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Impact of 5-HTCells · 2023
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. 2-Phenyl-1ACS chemical neuroscience · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Matthew BrodskyDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98104, USA; Department of Pharmacology, University of Washington, Seattle, WA 98104, USA; Graduate Program in Neuroscience, University of Washington, Seattle, WA 98104, USA.
Adam J LesiakDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98104, USA; Department of Pharmacology, University of Washington, Seattle, WA 98104, USA.
Alex CroicuDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98104, USA; Department of Pharmacology, University of Washington, Seattle, WA 98104, USA.
Nathalie CohencaDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98104, USA; Department of Pharmacology, University of Washington, Seattle, WA 98104, USA.
Jane M SullivanDepartment of Physiology & Biophysics, University of Washington, Seattle, WA 98104, USA; Graduate Program in Neuroscience, University of Washington, Seattle, WA 98104, USA.
John F NeumaierDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98104, USA; Department of Pharmacology, University of Washington, Seattle, WA 98104, USA. Electronic address: neumaier@uw.edu.
University of Washington · US

Funding

TRAINING IN THE MOLECULAR PHARMACOLOGY OF ABUSED DRUGST32DA007278 · NIDA · UNIVERSITY OF WASHINGTON · PI Susan Marie Ferguson, Paul E. M. Phillips · 1993 to 2026
$9.8M
Striatal 5-HT6 receptors, reward and addictionR01DA030807 · NIDA · UNIVERSITY OF WASHINGTON · PI NEUMAIER, JOHN F · 2011 to 2015
$1.7M
The Role of 5-HT6 Receptors in Primary Neuronal CiliaR21DA035577 · NIDA · UNIVERSITY OF WASHINGTON · PI NEUMAIER, JOHN F · 2013 to 2014
$381k
NIDA NIH HHS R01 DA030807NIDA NIH HHS R21 DA035577NIDA NIH HHS T32 DA007278
6 · The paper itself

Abstract

The 5-HT

Indexed as

AnimalsCells, CulturedCiliaCorpus StriatumDose-Response Relationship, DrugGene ExpressionMethylaminesMice, Inbred C57BLMice, KnockoutNeuronsPiperazinesPyridinesReceptors, SerotoninSerotonin AntagonistsSerotonin Receptor AgonistsSulfonamidesMethylaminesN-(2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo(2,3-b)pyridin-1-yl)ethyl)-N,N-dimethylaminePiperazinesPyridinesReceptors, SerotoninSB 399885serotonin 6 receptorSerotonin AntagonistsSerotonin Receptor AgonistsSulfonamides5-HT(6) receptorsPrimary ciliaPrimary cultured neuronsSerotoninSerotonin-6Striatum

Identifiers

PMID28087224
PMCPMC5392252
OpenAlexW2576623657

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.