ArticleBMC oral health2017
Association between Low blood lead levels and increased risk of dental caries in children: a cross-sectional study.
Article in BMC oral health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 28 citations in OpenAlex.
- Heavy metal exposure and dental caries in children and adolescents: a NHANES-based analysis integrating machine learning approaches.BMC pediatrics · 2026Article
- Environmental Determinants of Early Childhood Caries: A Narrative Synthesis of Observational Evidence and Implications for Global Policy.Dentistry journal · 2025Article
- Correlation Between Urinary Heavy Metals and Early Childhood Caries in a Typical Industrial and Mining Area.Biological trace element research · 2025Article
- Systematic Review of Lead Exposure and Its Effects on Caries and Aesthetics in Children and Adolescents.Healthcare (Basel, Switzerland) · 2025Review
- Effects of Blood Lead Levels <10 µg/dL in School-Age Children and Adolescents: A Scoping Review.Pediatrics · 2024Article
- A scoping review on the associations between early childhood caries and sustainable cities and communities using the sustainable development goal 11 framework.BMC oral health · 2024Article
- Metal mixtures and oral health among children and adolescents in the National Health and Nutrition Examination Survey (NHANES), 2017-2020.International journal of hygiene and environmental health · 2024Article
- Development and optimization of heavy metal lead biosensors in biomedical and environmental applications.Journal of the Chinese Medical Association : JCMA · 2021Review
- Oral antimicrobial activity weakened in children with electronic waste lead exposure.Environmental science and pollution research international · 2020Article
- Association Between Environmental Health, Ecosystem Vitality, and Early Childhood Caries.Frontiers in pediatrics · 2020Article
- Primary teeth microhardness and lead (Pb) levels.Heliyon · 2019Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective of this study was to examine the association between low blood lead levels of <5 μg/dL and the development of dental caries among children.
methodsThe Children's Health and Environment Research (CHEER) group recruited a cohort of 7,059 school-aged children from six Korean cities. The final study populations in the permanent and deciduous teeth groups were 1,564 and 1,241 children, respectively, after excluding 4 children with blood lead levels of >5 μg/dL. Compared with the children who did not have dental caries, the risk of having dental caries according to blood lead level was estimated by using the zero-inflated negative binomial model.
resultsThe geometric mean (geometric standard deviation, maximum) blood lead level was 1.53 μg/dL (1.57, 4.89 μg/dL), and 74.4% of children had a level of <2 μg/dL. Blood lead level was significantly higher in the children with than in those without deciduous dental caries (1.59 vs. 1.51 μg/dL), similarly with permanent dental caries (1.65 vs. 1.51 μg/dL). After adjustment for covariates, deciduous teeth surfaces that were decayed and filled increased significantly with increasing blood lead levels in a dose-dependent manner (prevalence ratio, 1.14; 95% confidence interval: 1.02-1.27). However, the risk of having dental caries in permanent teeth was not linearly associated with the increase in blood lead level.
conclusionsIn the sum of decayed and filled surfaces, we found a significant increase in risk of dental caries of the deciduous teeth with an increase in blood lead levels (<5 μg/dL) but found no statistical significance in the association with decayed and filled surfaces of caries separately.
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