Evidence map›Paper›PMID 28086859›Full record

ArticleBMC complementary and alternative medicine2017

Cheongsangbangpung-tang ameliorated the acute inflammatory response via the inhibition of NF-κB activation and MAPK phosphorylation.

Seon Young Kim, Sang Mi Park, Min Hwangbo, Jong Rok Lee, Sung Hui Byun, Sae Kwang Ku, Il Je Cho, Sang Chan Kim, Seon Young Jee, Sook Jahr Park

Open access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Anti-Inflammatory Effects ofLife (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Seon Young KimCollege of Korean Medicine, Daegu Haany University, 1 Haanydaero, Gyeongsan, 38610, Republic of Korea.
Sang Mi ParkCollege of Korean Medicine, Daegu Haany University, 1 Haanydaero, Gyeongsan, 38610, Republic of Korea.
Min HwangboCollege of Korean Medicine, Daegu Haany University, 1 Haanydaero, Gyeongsan, 38610, Republic of Korea.
Jong Rok LeeDepartment of Pharmaceutical Engineering, Daegu Haany University, 1 Haanydaero, Gyeongsan, 38610, Republic of Korea.
Sung Hui ByunCollege of Korean Medicine, Daegu Haany University, 1 Haanydaero, Gyeongsan, 38610, Republic of Korea.
Sae Kwang KuCollege of Korean Medicine, Daegu Haany University, 1 Haanydaero, Gyeongsan, 38610, Republic of Korea.
Il Je ChoCollege of Korean Medicine, Daegu Haany University, 1 Haanydaero, Gyeongsan, 38610, Republic of Korea.
Sang Chan KimCollege of Korean Medicine, Daegu Haany University, 1 Haanydaero, Gyeongsan, 38610, Republic of Korea.
Seon Young JeeCollege of Korean Medicine, Daegu Haany University, 1 Haanydaero, Gyeongsan, 38610, Republic of Korea. jeesy@dhu.ac.kr.
Sook Jahr ParkCollege of Korean Medicine, Daegu Haany University, 1 Haanydaero, Gyeongsan, 38610, Republic of Korea. haany@dhu.ac.kr.
Daegu Haany University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCheongsangbangpung-tang (CBT) is a traditional herbal formula used in Eastern Asia to treat heat-related diseases and swellings in the skin. The present study was conducted to evaluate the anti-inflammatory effects of cheongsangbangpung-tang extract (CBTE) both in vitro and in vivo.

methodsThe in vitro effects of CBTE on the lipopolysaccharide (LPS)-induced production of inflammation-related proteins were examined in RAW 264.7 cells. The levels of nitric oxide (NO) were measured with the Griess reagent. Inflammatory cytokines and prostaglandin E

resultsIn an in vitro study, CBTE inhibited the production of NO and PGE

conclusionsBased on these results, CBTE should favourably inhibit the acute inflammatory response through modulation of NF-κB activation and MAPK phosphorylation. Furthermore, the inhibition of CBTE in rat paw oedema induced by CA is considered to be clear evidence that CBTE may be a useful source to treat inflammation.

Indexed as

AnimalsAnti-Inflammatory AgentsCyclooxygenase 2EdemaHumansInterleukin-6MacrophagesMaleMiceMitogen-Activated Protein KinasesNF-kappa BNitric Oxide Synthase Type IIPhosphorylationPlant ExtractsRatsRats, Sprague-DawleyAnti-Inflammatory AgentsCyclooxygenase 2Interleukin-6Mitogen-Activated Protein KinasesNF-kappa BNitric Oxide Synthase Type IIPlant ExtractsCheongsangbangpung-tangInflammationMitogen-activated protein kinaseNuclear factor-kappaBPaw oedema

Identifiers

PMID28086859
PMCPMC5237186
OpenAlexW2579730125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.