Evidence map›Paper›PMID 28086854›Full record

ArticleBMC complementary and alternative medicine2017

In vitro assessment of hepatoprotective agents against damage induced by acetaminophen and CCl

Liliana Torres González, Noemí Waksman Minsky, Linda Elsa Muñoz Espinosa, Ricardo Salazar Aranda, Jonathan Pérez Meseguer, Paula Cordero Pérez

Open access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 66 citations in OpenAlex.

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  3. A novel polysaccharide ofFood chemistry: X · 2026
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  8. Robust anti-tubercular profile ofFrontiers in microbiology · 2024
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  10. Flavonoids ofSouth African journal of botany : official journal of the South African Association of Botanists = Suid-Afrikaanse tydskrif vir plantkunde : amptelike tydskrif van die Suid-Afrikaanse Genootskap van Plantkundiges · 2023
    Article
  11. Plants (Basel, Switzerland) · 2023
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  12. Article
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  15. Article
  16. Development of a Hepatoprotective Herbal Drug fromEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  17. Sage,Molecules (Basel, Switzerland) · 2021
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  18. Article
  19. Hepatoprotection ofAntioxidants (Basel, Switzerland) · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Liliana Torres GonzálezLiver Unit, Gastroenterology Service, Department of Internal Medicine, University Hospital "Dr. José E. González", Av. Gonzalitos #235 Col. Mitras Centro C.P., 64460, Monterrey, Nuevo León, Mexico.
Noemí Waksman MinskyDepartment of Analytical Chemistry, School of Medicine, Universidad Autónoma de Nuevo León, Av. Madero y Aguirre Pequeño S/N, Col. Mitras Centro, C. P., 64460, Monterrey, N. L., Mexico.
Linda Elsa Muñoz EspinosaLiver Unit, Gastroenterology Service, Department of Internal Medicine, University Hospital "Dr. José E. González", Av. Gonzalitos #235 Col. Mitras Centro C.P., 64460, Monterrey, Nuevo León, Mexico.
Ricardo Salazar ArandaDepartment of Analytical Chemistry, School of Medicine, Universidad Autónoma de Nuevo León, Av. Madero y Aguirre Pequeño S/N, Col. Mitras Centro, C. P., 64460, Monterrey, N. L., Mexico.
Jonathan Pérez MeseguerDepartment of Analytical Chemistry, School of Medicine, Universidad Autónoma de Nuevo León, Av. Madero y Aguirre Pequeño S/N, Col. Mitras Centro, C. P., 64460, Monterrey, N. L., Mexico.
Paula Cordero PérezLiver Unit, Gastroenterology Service, Department of Internal Medicine, University Hospital "Dr. José E. González", Av. Gonzalitos #235 Col. Mitras Centro C.P., 64460, Monterrey, Nuevo León, Mexico. paucordero@yahoo.com.mx.
Hospital Universitario Dr José Eleuterio Gonzalez · MXUniversidad Autónoma de Nuevo León · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn vitro bioassays are important in the evaluation of plants with possible hepatoprotective effects. The aims of this study were to evaluate the pretreatment of HepG2 cells with hepatoprotective agents against the damage induced by carbon tetrachloride (CCl

methodsAntioxidative activity was measured using an assay to measure 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging. The in vitro hepatotoxicity of CCl

resultsOnly SLB and SLM showed strong antioxidative activity in the DPPH assay (39.71 ± 0.85 μg/mL and 14.14 ± 0.65 μg/mL, respectively). CCl

conclusionsCCl

Indexed as

AcetaminophenAlanine TransaminaseAspartate AminotransferasesCarbon TetrachlorideCell SurvivalGlutathioneHep G2 CellsHumansLipid PeroxidationLiverMalondialdehydePlant ExtractsProtective AgentsAcetaminophenAlanine TransaminaseAspartate AminotransferasesCarbon TetrachlorideGlutathioneMalondialdehydePlant ExtractsProtective AgentsAcetaminophenCarbon tetrachlorideHepatoprotectiveHepG2 cell lineSilybininSilymarinSilyphos

Identifiers

PMID28086854
PMCPMC5234107
OpenAlexW2572794158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.