ArticleBMC plant biology2017
Genome-wide association analysis of seedling traits in diverse Sorghum germplasm under thermal stress.
Article in BMC plant biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 123 citations in OpenAlex.
- Meta-analysis identifies pleiotropic loci controlling phenotypic trade-offs in sorghum.Genetics · 2021Pooled it
- Investigating GERMs: how genotype, environment, and rhizosphere microbiome interactions underlie heat response in maize and sorghum.The New phytologist · 2026Article
- Pleiotropic SNPs and genes linked to enhanced seed longevity and vigor for climate resilient pearl millet production.Frontiers in plant science · 2026Article
- Investigating GERMs: How Genotype, Environment, and Rhizosphere Microbiome interactions underlie heat response in maize and sorghum.bioRxiv : the preprint server for biology · 2025Article
- Multi-locus genome-wide association studies for root system architectural traits in Ethiopian sorghum (Sorghum bicolor L.) landraces.BMC plant biology · 2025Article
- Advances in Functional Genomics for Exploring Abiotic Stress Tolerance Mechanisms in Cereals.Plants (Basel, Switzerland) · 2025Review
- Reproductive Cold Stress in Contrasting Sorghum Genotypes: Is Pollen Fertility Really the Crucial Trait?Plant direct · 2025Article
- Transcriptome Analysis Reveals the Pivotal Genes and Regulation Pathways Under Cold Stress and IdentifiesPlants (Basel, Switzerland) · 2025Article
- Role of functional genes for seed vigor related traits through genome-wide association mapping in finger millet (Eleusine coracana L. Gaertn.).Scientific reports · 2025Article
- Genome-wide association study and genomic prediction of root system architecture traits in Sorghum (Sorghum bicolor (L.) Moench) at the seedling stage.BMC plant biology · 2025Article
- Validation of sorghum quality control (QC) markers across African breeding lines.The plant genome · 2024Article
- Mapping the genetic architecture of low-temperature stress tolerance in citron watermelon.The plant genome · 2024Article
- Longitudinal genome-wide association study reveals early QTL that predict biomass accumulation under cold stress in sorghum.Frontiers in plant science · 2024Article
- Identification of pleiotropic loci mediating structural and non-structural carbohydrate accumulation within the sorghum bioenergy association panel using high-throughput markers.Frontiers in plant science · 2024Article
- Pilot-scale genome-wide association mapping in diverse sorghum germplasms identified novel genetic loci linked to major agronomic, root and stomatal traits.Scientific reports · 2023Article
- Genetic dissection of root architecture in Ethiopian sorghum landraces.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Transcriptomic and Hormone Analyses Provide Insight into the Regulation of Axillary Bud Outgrowth ofCurrent issues in molecular biology · 2023Article
- Recent advancements in the breeding of sorghum crop: current status and future strategies for marker-assisted breeding.Frontiers in genetics · 2023Review
- GWAS reveals novel loci and identifies aFrontiers in plant science · 2023Article
- Current advances in the molecular regulation of abiotic stress tolerance in sorghumFrontiers in plant science · 2023Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundClimate variability due to fluctuation in temperature is a worldwide concern that imperils crop production. The need to understand how the germplasm variation in major crops can be utilized to aid in discovering and developing breeding lines that can withstand and adapt to temperature fluctuations is more necessary than ever. Here, we analyzed the genetic variation associated with responses to thermal stresses in a sorghum association panel (SAP) representing major races and working groups to identify single nucleotide polymorphisms (SNPs) that are associated with resilience to temperature stress in a major cereal crop.
resultsThe SAP exhibited extensive variation for seedling traits under cold and heat stress. Genome-wide analyses identified 30 SNPs that were strongly associated with traits measured at seedling stage under cold stress and tagged genes that act as regulators of anthocyanin expression and soluble carbohydrate metabolism. Meanwhile, 12 SNPs were significantly associated with seedling traits under heat stress and these SNPs tagged genes that function in sugar metabolism, and ion transport pathways. Evaluation of co-expression networks for genes near the significantly associated SNPs indicated complex gene interactions for cold and heat stresses in sorghum. We focused and validated the expression of four genes in the network of Sb06g025040, a basic-helix-loop-helix (bHLH) transcription factor that was proposed to be involved in purple color pigmentation of leaf, and observed that genes in this network were upregulated during cold stress in a moderately tolerant line as compared to the more sensitive line.
conclusionThis study facilitated the tagging of genome regions associated with variation in seedling traits of sorghum under cold and heat stress. These findings show the potential of genotype information for development of temperature resilient sorghum cultivars and further characterization of genes and their networks responsible for adaptation to thermal stresses. Knowledge on the gene networks from this research can be extended to the other cereal crops to better understand the genetic basis of resilience to temperature fluctuations during plant developmental stages.
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