ArticleBMC microbiology2017
Methicillin resistance and virulence genes in invasive and nasal Staphylococcus epidermidis isolates from neonates.
Article in BMC microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 52 citations in OpenAlex.
- InJournal of bacteriology · 2026Article
- InbioRxiv : the preprint server for biology · 2026Article
- [Antibacterial activity and mechanism of the antiparasitic drug resorantel againstZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026Article
- Prevalence of Biofilm-Forming and Antibiotic-Resistant Coagulase-Negative Staphylococci Isolated from Hospitalized Patients in an Orthopedic Clinic.Pathogens (Basel, Switzerland) · 2026Article
- Biofilm Formation, c-di-GMP Production, and Antimicrobial Resistance in Staphylococcal Strains Isolated from Prosthetic Joint Infections: A Pilot Study in Total Hip and Knee Arthroplasty Patients.International journal of molecular sciences · 2025Article
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- The pathogenicity and virulence of the opportunistic pathogenVirulence · 2024Review
- Increase in methicillin-resistant Staphylococcus spp. colonization among pregnant individuals during COVID-19 pandemic.Scientific reports · 2024Article
- Extracellular G-quadruplexes and Z-DNA protect biofilms from DNase I, and G-quadruplexes form a DNAzyme with peroxidase activity.Nucleic acids research · 2024Article
- Resistome, mobilome, and virulome explored in clinical isolates derived from acne patients in Egypt: unveiling unique traits of an emerging coagulase-negativeFrontiers in cellular and infection microbiology · 2024Article
- The frequency of adherence, biofilm-associated, Arginine Catabolic Mobile element genes, and biofilm formation in clinical and healthcare worker coagulase-negative staphylococci isolates.BMC microbiology · 2023Article
- Molecular Detection and Characterization of theBioMed research international · 2023Article
- Clinical and Bacteriological Analyses of Biofilm-Forming Staphylococci Isolated from Diabetic Foot Ulcers.Infection and drug resistance · 2023Article
- Transcriptome Mining to Identify Molecular Markers for the Diagnosis ofAntibiotics (Basel, Switzerland) · 2022Article
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- Whole-Genome Sequence of Multidrug-Resistant Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2022Article
- Comparative profiling of agr locus, virulence, and biofilm-production genes of human and ovine non-aureus staphylococci.BMC veterinary research · 2022Article
- Look Who's Talking: Host and Pathogen Drivers ofInternational journal of molecular sciences · 2022Review
- Coagulase-Negative Staphylococci Clones Are Widely Distributed in the Hospital and Community.Pathogens (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStaphylococcus epidermidis is an opportunistic pathogen involved in hospital-acquired infections, particularly in those related to medical devices. This study characterized 50 genetically unrelated S. epidermidis isolates from bloodstream infections (BSIs, n = 31) and nares (n = 19) of neonates in relation to staphylococcal chromosomal cassette mec (SCCmec) type, biofilm production and associated genes, and the arginine catabolic mobile elements (ACME), in order to detect virulence factors that could discriminate a potential invasiveness isolate or predict an increasing pathogenicity.
resultsIsolates from both groups showed no difference for biofilm production and ACME genes detection. However, BSI isolates harbored more frequently the sdrF and sesI genes (p < 0.05), whereas biofilm producer isolates were associated with presence of the aap gene. The sdrF gene was also significantly more in the biofilm producer isolates from BSI. The SCCmec type IV and the ccr2 complex were related to BSI isolates (p < 0.05), while 83% of the nasal isolates were non-typeable for the SCCmec elements, with the mec complex and ccr undetectable as the most frequent profile.
conclusionsDespite the great clonal diversity displayed by S. epidermidis isolates from neonates, BSI isolates harbored more frequently the sdrF and sesI adhesin genes, while nasal isolates were very variable in SCCmec composition. These aspects could be advantageous to improve colonization in the host increasing its pathogenicity.
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