Evidence map›Paper›PMID 28086181›Full record

Trial reportPsychiatry research2017

Cognitive behavioral therapy for posttraumatic stress disorder in individuals with severe mental illness and borderline personality disorder.

M Alexandra Kredlow, Kristin L Szuhany, Stephen Lo, Haiyi Xie, Jennifer D Gottlieb, Stanley D Rosenberg, Kim T Mueser

2 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychiatry research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03833453 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Prediction and Outcome Study in PTSD and (Borderline) Personality Disorders

TypeinterventionalSponsorArkinRan2018 to 2023Enrolled126ConditionsPosttraumatic Stress Disorder (PTSD), Borderline Personality Disorder (BPD)ArmsEMDR, DBT
NCT03833531 nacompletednot on this mapstarted 2018, after this paper: background citation

Prediction and Outcome Study in PTSD and (Cluster C) Personality Disorders

TypeinterventionalSponsorArkinRan2018 to 2023Enrolled131ConditionsPosttraumatic Stress Disorder (PTSD), Avoidant Personality Disorder, Dependent Personality Disorder, Obsessive Compulsive Personality DisorderArmsImRS, SFT
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Psychological therapies for people with borderline personality disorder.The Cochrane database of systematic reviews · 2020
    Pooled it
  4. Article
  5. Review
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

M Alexandra KredlowDepartment of Psychological and Brain Sciences, Boston University, Boston, MA 02215, United States.
Kristin L SzuhanyDepartment of Psychological and Brain Sciences, Boston University, Boston, MA 02215, United States.
Stephen LoDepartment of Psychological and Brain Sciences, Boston University, Boston, MA 02215, United States.
Haiyi XieGeisel School of Medicine at Dartmouth, Hanover, NH 03755, United States.
Jennifer D GottliebCenter for Psychiatric Rehabilitation, Boston University, Boston, MA 02215, United States.
Stanley D RosenbergGeisel School of Medicine at Dartmouth, Hanover, NH 03755, United States.
Kim T MueserDepartment of Psychological and Brain Sciences, Boston University, Boston, MA 02215, United States; Center for Psychiatric Rehabilitation, Boston University, Boston, MA 02215, United States. Electronic address: mueser@bu.edu.
Boston University · USDartmouth College · US

Funding

Cognitive-Behavioral Treatment of PTSD in SMI ClientsR01MH064662 · NIMH · DARTMOUTH COLLEGE · PI MUESER, KIM T · 2002 to 2010
$3.7M
Exploring the Boundaries of Post-Retrieval Extinction in Anxious IndividualsF31MH103969 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI KREDLOW, MARIA ALEXANDRA G · 2014 to 2016
$104k
Efficacy of Adjunctive Exercise for the Behavioral Treatment of Major DepressionF31MH100773 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI SZUHANY, KRISTIN L. · 2013 to 2016
$93k
NIMH NIH HHS F31 MH100773NIMH NIH HHS F31 MH103969NIMH NIH HHS R01 MH064662
6 · The paper itself

Abstract

Secondary analyses were performed on data from two randomized controlled trials of a cognitive behavioral therapy (CBT) program for posttraumatic stress disorder (PTSD) in individuals with severe mental illness (SMI) to examine the feasibility, tolerability, and effectiveness for individuals with borderline personality disorder (BPD). In Study 1, 27 participants received CBT or treatment as usual. In Study 2, 55 participants received CBT or a Brief treatment. Feasibility and tolerability of CBT, PTSD symptoms, and other mental health and functional outcomes were examined, with assessments at baseline, post-treatment, and two follow-up time points. CBT was feasible and tolerable in this population. Study 1 participants in CBT improved significantly more in PTSD symptoms, depression, and self-reported physical health. Study 2 participants in both CBT and Brief improved significantly in PTSD symptoms, posttraumatic cognitions, depression, and overall functioning, with those in CBT acquiring significantly more PTSD knowledge, and having marginally significantly greater improvement in PTSD symptoms. CBT for PTSD was feasible and tolerated in individuals with SMI, BPD, and PTSD, and associated with improvements in PTSD symptoms and related outcomes. Prospective research is needed to evaluate CBT in individuals with BPD, including comparing it with staged interventions for this population.

Indexed as

AdultBorderline Personality DisorderCognitive Behavioral TherapyDepressionFeasibility StudiesFemaleHumansMaleMental DisordersMiddle AgedStress Disorders, Post-TraumaticTreatment Outcome

Identifiers

PMID28086181
PMCPMC5325773
OpenAlexW2570086898

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.