Evidence map›Paper›PMID 28085530›Full record

ArticleRenal failure2017

Invasive fungal infections in renal transplant patients: a single center study.

Minaxi H Patel, Rashmi D Patel, Aruna V Vanikar, Kamal V Kanodia, Kamlesh S Suthar, Lovelesh K Nigam, Himanshu V Patel, Ansy H Patel, Vivek B Kute, Hargovind L Trivedi

Abstract read
In one paragraph

Article in Renal failure, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Longitudinal assessment of the effect of invasive fungal infections on transplant success in kidney transplant recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  3. Review
  4. A Rare Case ofCase reports in transplantation · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Long-term follow-up of SARS-CoV-2 recovered renal transplant recipients: A single-center experience from India.Transplant infectious disease : an official journal of the Transplantation Society · 2021
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Minaxi H Patela Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology , IKDRC-ITS , Ahmedabad , India.
Rashmi D Patela Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology , IKDRC-ITS , Ahmedabad , India.
Aruna V Vanikara Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology , IKDRC-ITS , Ahmedabad , India.
Kamal V Kanodiaa Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology , IKDRC-ITS , Ahmedabad , India.
Kamlesh S Suthara Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology , IKDRC-ITS , Ahmedabad , India.
Lovelesh K Nigama Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology , IKDRC-ITS , Ahmedabad , India.
Himanshu V Patelb Department of Nephrology and Clinical Transplantation , Institute of Kidney Diseases and Research Center, Dr H.L. Trivedi Institute of Transplantation Sciences (IKDRC-ITS) , Ahmedabad , India.
Ansy H Patelb Department of Nephrology and Clinical Transplantation , Institute of Kidney Diseases and Research Center, Dr H.L. Trivedi Institute of Transplantation Sciences (IKDRC-ITS) , Ahmedabad , India.
Vivek B Kuteb Department of Nephrology and Clinical Transplantation , Institute of Kidney Diseases and Research Center, Dr H.L. Trivedi Institute of Transplantation Sciences (IKDRC-ITS) , Ahmedabad , India.
Hargovind L Trivedib Department of Nephrology and Clinical Transplantation , Institute of Kidney Diseases and Research Center, Dr H.L. Trivedi Institute of Transplantation Sciences (IKDRC-ITS) , Ahmedabad , India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTimely diagnosis of invasive fungal infections (IFI) in renal transplant (RT) patients on immunosuppression is often difficult, jeopardizing their life and graft. We reported IFI and their causative fungal agents in post-RT patients. MATERIALS AND

methodsThis was a retrospective 6-year clinical study carried out from 2010 to 2015 on 1900 RT patients. Clinical data included patient-donor demographics, time to onset of infection, risk factors and graft function in terms of serum creatinine (SCr). To identify IFI, we examined bronchoalveolar lavage (BAL), blood, tissue, and wound swab samples by conventional mycological methods.

resultsIFI were diagnosed in 30 (1.56%) patients on triple immunosuppression, mainly males (n = 25) with mean age of 36.57 ± 11.9 years at 13.12 ± 18.35 months post-RT. Aspergillus species was identified in 11 BAL, one tissue, and one wound specimen each, 30.76% of these were fatal and 15.38% caused graft loss; Candida albicans was in nine BAL, four blood, two wound swab, and one tissue specimens, 25% of these were fatal and 25% had graft loss and one mucor in BAL which was fatal. Seven patients were diabetic, 10 had superadded cytomegalovirus infection, and 15 were anti-rejected.

conclusionIFI are associated with increased morbidity and mortality in RT patients. Triple immunosuppression, broad spectrum antibiotics for ≥ two weeks, diabetes and superadded infection are added risks for these patients. Prevention, early diagnosis, and appropriate management are necessary to improve their prognosis.

Indexed as

Immunosuppression TherapyInvasive Fungal InfectionsKidney TransplantationPostoperative ComplicationsAdultAmphotericin BAntifungal AgentsAspergillusCandida albicansFemaleGraft SurvivalHumansIndiaKidney Failure, ChronicMaleMiddle AgedAmphotericin BAntifungal AgentsAspergillusCandida albicansInvasive fungal infectionMucorRenal transplant

Identifiers

PMID28085530
PMCPMC6014505

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.