ArticleThe Journal of cell biology1989
Viscoelasticity of F-actin measured with magnetic microparticles.
Article in The Journal of cell biology, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Directed manipulation of membrane proteins by fluorescent magnetic nanoparticles.Nature communications · 2020Article
- Biomembrane-mimicking lipid bilayer system as a mechanically tunable cell substrate.Biomaterials · 2014Article
- Magnetic tweezers: micromanipulation and force measurement at the molecular level.Biophysical journal · 2002Article
- Sound attenuation of polymerizing actin reflects supramolecular structures: viscoelastic properties of actin gels modified by cytochalasin D, profilin and alpha-actinin.The Biochemical journal · 2001Article
- Cell sorting is analogous to phase ordering in fluids.Proceedings of the National Academy of Sciences of the United States of America · 2000Article
- Magnetic phagosome motion in J774A.1 macrophages: influence of cytoskeletal drugs.Biophysical journal · 2000Article
- Cryoatomic force microscopy of filamentous actin.Biophysical journal · 2000Article
- Viscoelastic properties of living embryonic tissues: a quantitative study.Biophysical journal · 1998Article
- Viscoelastic response of fibroblasts to tension transmitted through adherens junctions.Biophysical journal · 1997Article
- Shear field mapping in actin networks by using magnetic tweezers.European biophysics journal : EBJ · 1996Article
- Local measurements of viscoelastic moduli of entangled actin networks using an oscillating magnetic bead micro-rheometer.Biophysical journal · 1994Article
- Control of cytoskeletal mechanics by extracellular matrix, cell shape, and mechanical tension.Biophysical journal · 1994Article
- Passive mechanical behavior of human neutrophils: power-law fluid.Biophysical journal · 1993Article
- Behaviour of magnetic micro-particles in the human lung.Radiation and environmental biophysics · 1993Article
- Mathematical model for the effects of adhesion and mechanics on cell migration speed.Biophysical journal · 1991Article
- Liquid crystal domains and thixotropy of filamentous actin suspensions.Proceedings of the National Academy of Sciences of the United States of America · 1990Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Dispersed submicroscopic magnetic particles were used to probe viscoelasticity for cytoplasm and purified components of cytoplasm. An externally applied magnetic field exerted force on particles in cells, in filamentous actin (F-actin) solutions, or in F-actin gels formed by the addition of the actin gelation factor, actin-binding protein (ABP). The particle response to magnetic torque can be related to the viscoelastic properties of the fluids. We compared data obtained on F-actin by the magnetic particle method with data obtained on F-actin by means of a sliding plane viscoelastometer. F-actin solutions had a significant elasticity, which increased by 20-fold when gels were formed by ABP addition. Both methods gave consistent results, but the dispersed magnetic particles indicated quantitatively greater rigidity than the viscoelastometer (two and six times greater for F-actin solutions and for F-actin plus ABP gels, respectively). These differences may be due to the fact that, compared with traditional microrheometers, dispersed particle measurements are less affected by long-range heterogeneity or domain-like structure. The magnetometric method was used to examine the mechanical properties of cytoplasm within intact macrophages; the application of the same magnetometric technique to both cells and well-defined, purified protein systems is a first step toward interpreting the results obtained for living cells in molecular terms. The magnetic particle probe system is an effective nonoptical technique for determining the motile and mechanical properties of cells in vitro and in vivo.
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