Evidence map›Paper›PMID 28085224›Full record

ReviewMolecular oncology2017

Modes of invasion during tumour dissemination.

Pahini Pandya, Jose L Orgaz, Victoria Sanz-Moreno

Abstract readReview
In one paragraph

Review in Molecular oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed.

  1. Article
  2. Review
  3. Amoeboid cancer cells at a glance.Journal of cell science · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. The activation of INF2 by Piezo1/CaCurrent biology : CB · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Leader Cells: Invade and Evade-The Frontline of Cancer Progression.International journal of molecular sciences · 2024
    Review
  18. Non-Muscle Myosin II A: Friend or Foe in Cancer?International journal of molecular sciences · 2024
    Review
  19. Review
  20. Article

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pahini PandyaTumour Plasticity Team, Randall Division of Cell and Molecular Biophysics, King's College London, UK.
Jose L OrgazTumour Plasticity Team, Randall Division of Cell and Molecular Biophysics, King's College London, UK.
Victoria Sanz-MorenoTumour Plasticity Team, Randall Division of Cell and Molecular Biophysics, King's College London, UK.

Funding

Cancer Research UK 12065Cancer Research UK 24478
6 · The paper itself

Abstract

Cancer cell migration and invasion underlie metastatic dissemination, one of the major problems in cancer. Tumour cells exhibit a striking variety of invasion strategies. Importantly, cancer cells can switch between invasion modes in order to cope with challenging environments. This ability to switch migratory modes or plasticity highlights the challenges behind antimetastasis therapy design. In this Review, we present current knowledge on different tumour invasion strategies, the determinants controlling plasticity and arising therapeutic opportunities. We propose that targeting master regulators controlling plasticity is needed to hinder tumour dissemination and metastasis.

Indexed as

Cell MovementActomyosinAnimalsEpithelial-Mesenchymal TransitionHumansNeoplasm InvasivenessNeoplasmsrho GTP-Binding ProteinsSignal TransductionActomyosinrho GTP-Binding Proteinsactomyosin contractilitycancer metastasisinvasionplasticityRho GTPases

Identifiers

PMID28085224
PMCPMC5423224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.