Evidence map›Paper›PMID 28085163›Full record

ArticleChemical communications (Cambridge, England)2017

PSMA-targeted contrast agents for intraoperative imaging of prostate cancer.

Kai Bao, Jeong Heon Lee, Homan Kang, G Kate Park, Georges El Fakhri, Hak Soo Choi

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Advances in PSMA-targeted therapy for prostate cancer.Prostate cancer and prostatic diseases · 2022
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. A Fluorescent, [ACS chemical biology · 2019
    Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kai BaoGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, MA 02114, USA. hchoi12@mgh.harvard.edu.
Jeong Heon Lee
Homan Kang
G Kate Park
Georges El Fakhri
Hak Soo Choi

Funding

Image-Guided Surgery of Endocrine Glands and Their Tumors using Near-Infrared FluR01EB011523 · NIBIB · BETH ISRAEL DEACONESS MEDICAL CENTER · PI CHOI, HAK SOO · 2010 to 2013
$2.0M
PEG-like Multimodal Nanoprobes for Imaging Enhanced Permeability RetentionR01EB017699 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI NORMANDIN, MARC DAVID · 2014 to 2017
$1.6M
NIBIB NIH HHS R01 EB011523NIBIB NIH HHS R01 EB017699
6 · The paper itself

Abstract

Prostate-specific membrane antigen (PSMA) can serve as a molecular cell surface target for the detection and treatment of prostate cancer. Near-infrared (NIR) fluorescence imaging enables highly sensitive, rapid, and non-radioactive imaging of PSMA, though specific targeting still remains a challenge because no optimized contrast agents exist.

Indexed as

Optical ImagingAnimalsAntigens, SurfaceContrast MediaGlutamate Carboxypeptidase IIHumansMaleMiceMolecular StructureNeoplasms, ExperimentalProstatic NeoplasmsAntigens, SurfaceContrast MediaFOLH1 protein, humanGlutamate Carboxypeptidase II

Identifiers

PMID28085163
PMCPMC5728657

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.