ArticleThe Journal of cell biology1989
High-mobility group protein HMG-I localizes to G/Q- and C-bands of human and mouse chromosomes.
Article in The Journal of cell biology, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed, 138 citations in OpenAlex.
- Revisiting the question: When is a centromere not a kinetochore?Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2025Review
- HMGA2 directly mediates chromatin condensation in association with neuronal fate regulation.Nature communications · 2023Article
- Nuclear High Mobility Group A2 (HMGA2) Interactome Revealed by Biotin Proximity Labeling.International journal of molecular sciences · 2023Article
- HMGA2 drives the IGFBP1/AKT pathway to counteract the increase in P27KIP1 protein levels in mtDNA/RNA-less cancer cells.Cancer science · 2023Article
- The Linker Histone GH1-HMGA1 Is Involved in Telomere Stability and DNA Damage Repair.Plant physiology · 2018Article
- Binding of high mobility group A proteins to the mammalian genome occurs as a function of AT-content.PLoS genetics · 2017Article
- Article
- Mechanisms of therapeutic resistance in cancer (stem) cells with emphasis on thyroid cancer cells.Frontiers in endocrinology · 2014Review
- Cross-linking of DNA through HMGA1 suggests a DNA scaffold.Nucleic acids research · 2011Article
- Article
- Optimal transactivation by Epstein-Barr nuclear antigen 1 requires the UR1 and ATH1 domains.Journal of virology · 2009Article
- High-dose intravenous immunoglobulin G improves systemic inflammation in a rat model of CLP-induced sepsis.Intensive care medicine · 2008Article
- Cell cycle-dependent binding of HMGN proteins to chromatin.Molecular biology of the cell · 2008Article
- Arabidopsis chromatin-associated HMGA and HMGB use different nuclear targeting signals and display highly dynamic localization within the nucleus.The Plant cell · 2006Article
- The amino terminus of Epstein-Barr Virus (EBV) nuclear antigen 1 contains AT hooks that facilitate the replication and partitioning of latent EBV genomes by tethering them to cellular chromosomes.Journal of virology · 2004Article
- Metaphase chromosome tethering is necessary for the DNA synthesis and maintenance of oriP plasmids but is insufficient for transcription activation by Epstein-Barr nuclear antigen 1.Journal of virology · 2003Article
- Association of chromatin proteins high mobility group box (HMGB) 1 and HMGB2 with mitotic chromosomes.Molecular biology of the cell · 2003Article
- DNA binding mediated by the wheat HMGa protein: a novel instance of selectivity against alternating GC sequence.Plant molecular biology · 2001Article
- Maintenance of Epstein-Barr virus (EBV) oriP-based episomes requires EBV-encoded nuclear antigen-1 chromosome-binding domains, which can be replaced by high-mobility group-I or histone H1.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Chromosomal proteins HMG-14 and HMG-17 are released from mitotic chromosomes and imported into the nucleus by active transport.The Journal of cell biology · 1998Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mammalian metaphase chromosomes can be identified by their characteristic banding pattern when stained with Giemsa dye after brief proteolytic digestion. The resulting G-bands are known to contain regions of DNA enriched in A/T residues and to be the principal location for the L1 (or Kpn 1) family of long interspersed repetitive sequences in human chromosomes. Here we report that antibodies raised against a highly purified and biochemically well characterized nonhistone "High-Mobility Group" protein, HMG-I, specifically localize this protein to the G-bands in mammalian metaphase chromosomes. In some preparations in which chromosomes are highly condensed, HMG-I appears to be located at the centromere and/or telomere regions of mammalian chromosomes as well. To our knowledge, this is the first well-characterized mammalian protein that localizes primarily to G-band regions of chromosomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.