Evidence map›Paper›PMID 28084653›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2017

Predicting early symptomatic osteoarthritis in the human knee using machine learning classification of magnetic resonance images from the osteoarthritis initiative.

Beth G Ashinsky, Mustapha Bouhrara, Christopher E Coletta, Benoit Lehallier, Kenneth L Urish, Ping-Chang Lin, Ilya G Goldberg, Richard G Spencer

Abstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Beth G AshinskyLaboratory of Clinical Investigation, Magnetic Resonance Imaging and Spectroscopy Section, National Institute on Aging, NIH, 251 Bayview Boulevard, Baltimore 21224, Maryland.
Mustapha BouhraraLaboratory of Clinical Investigation, Magnetic Resonance Imaging and Spectroscopy Section, National Institute on Aging, NIH, 251 Bayview Boulevard, Baltimore 21224, Maryland.
Christopher E ColettaImage Informatics and Computational Biology Unit, National Institute on Aging, NIH, Baltimore, Maryland.
Benoit LehallierDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California.
Kenneth L UrishBone and Joint Center, Magee Women's Hospital, Department of Orthopaedic Surgery, Pittsburgh, Pennsylvania.
Ping-Chang LinDepartment of Radiology, College of Medicine, Howard University, Washington, DC, Washington.
Ilya G GoldbergImage Informatics and Computational Biology Unit, National Institute on Aging, NIH, Baltimore, Maryland.
Richard G SpencerLaboratory of Clinical Investigation, Magnetic Resonance Imaging and Spectroscopy Section, National Institute on Aging, NIH, 251 Bayview Boulevard, Baltimore 21224, Maryland.

Funding

University of Pittsburgh Clinical and Translational Science InstitutionKL2TR000146 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$8.7M
Improving Sensitivity and Specificity of Parametric MRI Assessment of CartilageZIAAG000922 · NIA · NATIONAL INSTITUTE ON AGING · PI SPENCER, RICHARD · 2009 to 2017
$6.3M
NMR STUDIES OF PHYSIOLOGY AND BIOCHEMISTRY IN CELLS, ORGANS AND ANIMALSZ01AG000381 · NIA · AGING · PI SPENCER, RICHARD · 1991 to 2007
$1.0M
Intramural NIH HHS Z01 AG000381NCATS NIH HHS KL2 TR000146
6 · The paper itself

Abstract

The purpose of this study is to evaluate the ability of a machine learning algorithm to classify in vivo magnetic resonance images (MRI) of human articular cartilage for development of osteoarthritis (OA). Sixty-eight subjects were selected from the osteoarthritis initiative (OAI) control and incidence cohorts. Progression to clinical OA was defined by the development of symptoms as quantified by the Western Ontario and McMaster Universities Arthritis (WOMAC) questionnaire 3 years after baseline evaluation. Multi-slice T CLINICAL SIGNIFICANCE: Machine learning algorithms applied to T

Indexed as

Machine LearningMagnetic Resonance ImagingAlgorithmsCartilage, ArticularCohort StudiesHumansMiddle AgedOsteoarthritis, KneeRegression AnalysisclassificationMRIosteoarthritispattern recognitionregistrationsegmentation

Identifiers

PMID28084653
PMCPMC5969573

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.