Evidence map›Paper›PMID 28084592›Full record

ArticleMolecular neurobiology2018

Maternal Hypermethioninemia Affects Neurons Number, Neurotrophins Levels, Energy Metabolism, and Na

Bruna M Schweinberger, André F Rodrigues, Elias Turcatel, Paula Pierozan, Leticia F Pettenuzzo, Mateus Grings, Giselli Scaini, Mariana M Parisi, Guilhian Leipnitz, Emilio L Streck and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Bruna M SchweinbergerPostgraduate Program in Biological Sciences-Biochemistry, Department of Biochemistry, Institute of Health Basic Sciences, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, CEP, Porto Alegre, RS, 90035-003, Brazil.
André F RodriguesPostgraduate Program in Biological Sciences-Biochemistry, Department of Biochemistry, Institute of Health Basic Sciences, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, CEP, Porto Alegre, RS, 90035-003, Brazil.
Elias TurcatelPostgraduate Program in Biological Sciences-Biochemistry, Department of Biochemistry, Institute of Health Basic Sciences, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, CEP, Porto Alegre, RS, 90035-003, Brazil.
Paula PierozanPostgraduate Program in Biological Sciences-Biochemistry, Department of Biochemistry, Institute of Health Basic Sciences, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, CEP, Porto Alegre, RS, 90035-003, Brazil.
Leticia F PettenuzzoPostgraduate Program in Biological Sciences-Biochemistry, Department of Biochemistry, Institute of Health Basic Sciences, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, CEP, Porto Alegre, RS, 90035-003, Brazil.
Mateus GringsPostgraduate Program in Biological Sciences-Biochemistry, Department of Biochemistry, Institute of Health Basic Sciences, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, CEP, Porto Alegre, RS, 90035-003, Brazil.
Giselli ScainiPostgraduate program in Health Sciences, Laboratory of Bioenergetics, University of Southern Santa Catarina, Criciúma, SC, Brazil.
Mariana M ParisiPostgraduate Program in Biological Sciences-Biochemistry, Department of Biochemistry, Institute of Health Basic Sciences, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, CEP, Porto Alegre, RS, 90035-003, Brazil.
Guilhian LeipnitzPostgraduate Program in Biological Sciences-Biochemistry, Department of Biochemistry, Institute of Health Basic Sciences, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, CEP, Porto Alegre, RS, 90035-003, Brazil.
Emilio L StreckPostgraduate program in Health Sciences, Laboratory of Bioenergetics, University of Southern Santa Catarina, Criciúma, SC, Brazil.
Florencia M Barbé-TuanaPostgraduate Program in Biological Sciences-Biochemistry, Department of Biochemistry, Institute of Health Basic Sciences, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, CEP, Porto Alegre, RS, 90035-003, Brazil.
Angela T S WysePostgraduate Program in Biological Sciences-Biochemistry, Department of Biochemistry, Institute of Health Basic Sciences, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2600-Anexo, CEP, Porto Alegre, RS, 90035-003, Brazil. wyse@ufrgs.br.
Universidade Federal do Rio Grande do Sul · BRBioEnergetics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the current study, we verified the effects of maternal hypermethioninemia on the number of neurons, apoptosis, nerve growth factor, and brain-derived neurotrophic factor levels, energy metabolism parameters (succinate dehydrogenase, complex II, and cytochrome c oxidase), expression and immunocontent of Na

Indexed as

Amino Acid Metabolism, Inborn ErrorsAnimalsBrainCell CountEnergy MetabolismFemaleGlycine N-MethyltransferaseMethionineNerve Growth FactorsNeuronsOxidation-ReductionPregnancyPrenatal Exposure Delayed EffectsRatsRats, WistarSodium-Potassium-Exchanging ATPaseGlycine N-MethyltransferaseMethionineNerve Growth FactorsSodium-Potassium-Exchanging ATPaseBrainEnergy metabolismMaternal hypermethioninemiaNa+,K+-ATPaseNeurons numberNeurotrophins

Identifiers

PMID28084592
OpenAlexW2574706259

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.