Evidence map›Paper›PMID 28084445›Full record

ArticleScientific reports2017

TFEB-mediated increase in peripheral lysosomes regulates store-operated calcium entry.

Luigi Sbano, Massimo Bonora, Saverio Marchi, Federica Baldassari, Diego L Medina, Andrea Ballabio, Carlotta Giorgi, Paolo Pinton

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 44 citations in OpenAlex.

  1. TFEB Deficiency Impairs Male Fertility Through Mitochondrial Dysfunction.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  2. TFEB and MCOLN1 are important forFrontiers in cellular and infection microbiology · 2026
    Article
  3. Article
  4. Review
  5. Organelle Communication with the Nucleus.Results and problems in cell differentiation · 2024
    Review
  6. Store-Operated CaJournal of clinical medicine · 2023
    Review
  7. Article
  8. TRPML1-Induced Lysosomal CaInternational journal of molecular sciences · 2023
    Article
  9. Intracellular CaFrontiers in physiology · 2023
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Lysosomal agents inhibit store-operated CaJournal of cell science · 2021
    Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Luigi SbanoDept. of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, 44121, Italy.
Massimo BonoraDept. of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, 44121, Italy.
Saverio MarchiDept. of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, 44121, Italy.
Federica BaldassariDept. of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, 44121, Italy.
Diego L MedinaTelethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Naples, Italy.
Andrea BallabioTelethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Naples, Italy.
Carlotta GiorgiDept. of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, 44121, Italy.
Paolo PintonDept. of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, 44121, Italy.
University of Ferrara · ITTelethon Institute Of Genetics And Medicine · ITTexas Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lysosomes are membrane-bound organelles mainly involved in catabolic processes. In addition, lysosomes can expel their contents outside of the cell via lysosomal exocytosis. Some of the key steps involved in these important cellular processes, such as vesicular fusion and trafficking, require calcium (Ca

Indexed as

AequorinBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsBiological TransportCalciumCalcium SignalingCell MembraneEndoplasmic ReticulumGene ExpressionGene Expression RegulationGene Knockdown TechniquesHeLa CellsHumansLysosomesSignal TransductionAequorinBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCalciumTFEB protein, human

Identifiers

PMID28084445
PMCPMC5233950
OpenAlexW2574751910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.