ArticleScientific reports2017
Common risk variants for colorectal cancer: an evaluation of associations with age at cancer onset.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023Guideline
- Colorectal Polyp Occurrence Associated With the ZMIZ1-AS1 rs704017 Variant and Hypertension Among Taiwan Biobank Participants.Cancer medicine · 2026Article
- ZMIZ1 promotes aerobic glycolysis and development of hepatocellular carcinoma through inducing NOTCH1-mediated transcription of PYCR1.Journal of translational medicine · 2026Article
- Allele frequency trajectories across age groups reveal ongoing natural selection shaping disease susceptibility.American journal of human genetics · 2026Article
- ALKBH5 demethylation modification of SE-lncRNA ZMIZ1-AS1 promotes FGFR1-mediated proliferation and invasive metastasis in osteosarcoma.Cellular and molecular life sciences : CMLS · 2025Article
- ZMIZ1 Regulates Proliferation, Autophagy and Apoptosis of Colon Cancer Cells by Mediating Ubiquitin-Proteasome Degradation of SIRT1.Biochemical genetics · 2024Article
- Dissecting the pathogenic effects of smoking and its hallmarks in blood DNA methylation on colorectal cancer risk.British journal of cancer · 2023Article
- Genome-wide association study of colorectal polyps identified highly overlapping polygenic architecture with colorectal cancer.Journal of human genetics · 2022Article
- Prostate Cancer Susceptibility Loci Identified inInternational journal of genomics · 2022Article
- Article
- Cumulative Burden of Colorectal Cancer-Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer.Gastroenterology · 2020Observational
- Evaluation of gene-environment interactions for colorectal cancer susceptibility loci using case-only and case-control designs.BMC cancer · 2019Article
- 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population.Nature communications · 2019Article
- Genetic Risk Score, Combined Lifestyle Factors and Risk of Colorectal Cancer.Cancer research and treatment · 2019Article
- Observational
- Effects of interactions between common genetic variants and alcohol consumption on colorectal cancer risk.Oncotarget · 2018Article
- Adenoma Detection before and after the age of 50: a retrospective analysis of Lebanese outpatients.BMJ open gastroenterology · 2018Article
- Effects of interactions between common genetic variants and smoking on colorectal cancer.BMC cancer · 2017Article
- A five-gene based risk score with high prognostic value in colorectal cancer.Oncology letters · 2017Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Common genetic risk variants for colorectal cancer (CRC) have been identified at approximately 40 loci by genome-wide association studies (GWAS). We investigated the association of these risk variants by age at onset of CRC using case-only and case-control analysis. A total of 1,962 CRC cases and 2,668 controls from two independent case-control studies conducted by Korea's National Cancer Center were included in this study. We genotyped 33 GWAS-identified single-nucleotide polymorphisms (SNPs) associated with CRC risk. The risk allele in SNP rs704017, located at 10q22.3 in the ZMIZ1-AS1 gene, was consistently less frequent among CRC patients aged <50 years than among CRC patients aged ≥50 years in the case-only analysis (odds ratio (OR) = 0.78, 95% confidence interval (CI) = 0.66-0.92, P = 2.7 × 10
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