Evidence map›Paper›PMID 28084330›Full record

ArticleCell research2017

CRISPR control of virulence in Pseudomonas aeruginosa.

Blake Wiedenheft, Joseph Bondy-Denomy

Abstract readComment
In one paragraph

Article in Cell research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Blake WiedenheftDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, USA.
Joseph Bondy-DenomyDepartment of Microbiology and Immunology, University of California San Francisco, San Francisco, CA, USA.

Funding

Discovering New Roles for CRISPR-Cas in Bacterial PathogenesisDP5OD021344 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BONDY-DENOMY, JOSEPH · 2015 to 2019
$2.1M
Structure and function of CRISPR RNA-guided foreign DNA surveillance systems in P. aeruginosaR01GM110270 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI WIEDENHEFT, BLAKE A · 2016 to 2019
$1.2M
NIGMS NIH HHS R01 GM110270NIH HHS DP5 OD021344
6 · The paper itself

Abstract

Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated genes (cas) are essential components of an adaptive immune system that protects bacteria and archaea from viral infection. Now a recent paper published in Cell Research suggests that the Type I-F immune system in Pseudomonas aeruginosa may also be involved in post-transcriptional regulation of virulence.

Indexed as

Clustered Regularly Interspaced Short Palindromic RepeatsAnimalsCRISPR-Cas SystemsPseudomonasPseudomonas aeruginosaVirulence

Identifiers

PMID28084330
PMCPMC5339854

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.