ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2020
Left ventricular eccentricity index measured with SPECT myocardial perfusion imaging: An additional parameter of adverse cardiac remodeling.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- The Role of Motion Correction Tools in Left Ventricular Functional Parameters Measured by Gated [Diagnostics (Basel, Switzerland) · 2026Article
- Left ventricular sphericity indexes by gated single photon emission computed tomography myocardial perfusion imaging: potential opportunities and challenges for cardiac remodeling and clinical prognosis-a narrative review.Quantitative imaging in medicine and surgery · 2025Review
- Assessment of Left Ventricular Shape Index and Eccentricity Index as Promising Parameters for Detection of Left Ventricular Remodeling in Cardiovascular Events.Current cardiology reviews · 2025Review
- Realistic Aspects of Cardiac Ultrasound in Rats: Practical Tips for Improved Examination.Journal of imaging · 2024Review
- Prognostic Value of Resting Left Ventricular Sphericity Indexes in Coronary Artery Disease With Preserved Ejection Fraction.Journal of the American Heart Association · 2024Article
- Spherization indices measured by resting SPECT improve risk stratification in patients with ischemia with non-obstructive coronary artery disease (INOCA).EJNMMI research · 2024Article
- Association of Long Noncoding RNA Expression Signatures with Stress-Induced Myocardial Perfusion Defects.Biomolecules · 2023Article
- Feasibility of Left Ventricle Lead Implantation in Cardiac Resynchronization Therapy Guided by Gated SPECT and Ventricular Remodeling.Arquivos brasileiros de cardiologia · 2023Article
- Cardiac remodelling in association with left ventricular dyssynchrony and systolic dysfunction in patients with coronary artery disease.Clinical physiology and functional imaging · 2022Article
- Incremental value of left ventricular shape parameters measured by gated SPECT MPI in predicting the super-response to CRT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Quantitation of Poststress Change in Ventricular Morphology Improves Risk Stratification.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021Article
- Associations of left ventricular shape with left ventricular volumes and functions assessed by ECG-gated SPECT in patients without significant perfusion abnormality.Heart and vessels · 2020Article
- Automatic evaluation of myocardial perfusion on SPECT: Need for "Normality".Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Stress-induced alteration of left ventricular eccentricity: An additional marker of multivessel CAD.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Evaluation data about accuracy of cadmium-zinc-telluride imaging in detecting single and multivessel coronary artery disease: Focus on gender differences.Data in brief · 2018Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSingle-photon emission computed-tomography (SPECT) allows the quantification of LV eccentricity index (EI), a measure of cardiac remodeling. We sought to evaluate the feasibility of EI measurement with SPECT myocardial perfusion imaging and its interactions with relevant LV functional and structural parameters. METHODS AND
resultsFour-hundred and fifty-six patients underwent myocardial perfusion imaging on a Cadmium-Zinc-Telluride (CZT) camera. The summed rest, stress, and difference scores were calculated. From rest images, the LV end-diastolic (EDV) and end-systolic volumes, ejection fraction (EF), and peak filling rate (PFR) were calculated. In every patient, the EI, ranging from 0 (sphere) to 1 (line), was computed using a dedicated software (QGS/QPS; Cedars-Sinai Medical Center). Three-hundred and thirty-eight/456 (74%) patients showed a normal EF (>50%), while 26% had LV systolic dysfunction. The EI was computed from CZT images with excellent reproducibility (interclass correlation coefficient: 0.99, 95% CI 0.98-0.99). More impaired EI values correlated with the presence of a more abnormal LV perfusion (P < .001), function (EF and PFR, P < .001), and structure (EDV, P < .001). On multivariate analysis, higher EDV (P < .001) and depressed EF (P = .014) values were independent predictors of abnormal EI.
conclusionsThe evaluation of LV eccentricity is feasible on gated CZT images. Abnormal EI associates with significant cardiac structural and functional abnormalities.
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