Evidence map›Paper›PMID 28083713›Full record

ArticleInternational urogynecology journal2017

Is levator hiatus distension associated with peripheral ligamentous laxity during pregnancy?

Bertrand Gachon, Xavier Fritel, Laetitia Fradet, Arnaud Decatoire, Patrick Lacouture, Henri Panjo, Fabrice Pierre, David Desseauve

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Article in International urogynecology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Bertrand GachonDepartment of Obstetrics and Gynecology, La Miletrie University Hospital, 2 rue de la Milétrie CS90577, 86021, Poitiers Cedex, France. bertrand.gachon@gmail.com.ORCID http://orcid.org/0000-0002-5772-6828
Xavier FritelDepartment of Obstetrics and Gynecology, La Miletrie University Hospital, 2 rue de la Milétrie CS90577, 86021, Poitiers Cedex, France.
Laetitia FradetP' Institute - RoBioSS Unit, Poitiers University - ENSMA, CNRS UPR 3346, Futuroscope, France.
Arnaud DecatoireP' Institute - RoBioSS Unit, Poitiers University - ENSMA, CNRS UPR 3346, Futuroscope, France.
Patrick LacoutureP' Institute - RoBioSS Unit, Poitiers University - ENSMA, CNRS UPR 3346, Futuroscope, France.
Henri PanjoINSERM, Center for Research in Epidemiology and Population Health (CESP), U1018, Gender, Sexuality and Health Team, Paris-Sud University, UMRS 1018, Villejuif, France.
Fabrice PierreDepartment of Obstetrics and Gynecology, La Miletrie University Hospital, 2 rue de la Milétrie CS90577, 86021, Poitiers Cedex, France.
David DesseauveDepartment of Obstetrics and Gynecology, La Miletrie University Hospital, 2 rue de la Milétrie CS90577, 86021, Poitiers Cedex, France.
Centre National de la Recherche Scientifique · FRUniversité Paris-Sud · FRLaboratoire de Génétique Cellulaire · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisThe impact of pregnancy on pelvic floor disorders remains poorly understood. During pregnancy, an increase in ligamentous laxity and pelvic organ mobility is often reported. Our main objective was to investigate a possible association between peripheral ligamentous laxity and levator hiatus (LH) distension during pregnancy.

methodsThis was a prospective longitudinal study of 26 pregnant women followed up from the first to the third trimester. We collected the following information: occurrence of pelvic organ prolapse (POP) symptoms (score higher than 0 for the POP section of the Pelvic Floor Distress Inventory 20 questions score), 4D perineal ultrasound scan results with LH distension assessment and measurement of metacarpophalangeal joint mobility (MCP laxity). The association between MCP laxity and LH distension was estimated by mixed multilevel linear regression. The associations between MCP laxity and categorical parameters were estimated in a multivariate analysis using a generalized estimating equation model.

resultsMCP laxity and LH distension were correlated with a correlation coefficient of 0.26 (p = 0.02), and 6.8% of the LH distension variance was explained by MCP laxity. In the multivariate analysis, MCP laxity was associated with POP symptoms with an odds ratio at 1.05 (95% CI 1.01-1.11) for an increase of 1° in MCP laxity.

conclusionLH distension and peripheral ligamentous laxity are significantly associated during pregnancy. However, the relationship is weak, and the results need to be confirmed in larger populations and with more specific techniques such as elastography to directly assess the elastic properties of the pelvic floor muscles.

Indexed as

AdultFemaleHumansJoint InstabilityLigamentsLongitudinal StudiesMuscle, SkeletalPelvic FloorPelvic Floor DisordersPerineumPregnancyPregnancy ComplicationsPregnancy TrimestersProspective StudiesUltrasonography, PrenatalLevator hiatusLigamentous laxityPelvic floorPelvic floor disordersPregnancy

Identifiers

PMID28083713
OpenAlexW2572299029

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.