Evidence map›Paper›PMID 28083690›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2017

The

Lorenza Scarpa, Sabine Buxbaum, Dorota Kendler, Katharina Fink, Jasmin Bektic, Leonhard Gruber, Clemens Decristoforo, Christian Uprimny, Peter Lukas, Wolfgang Horninger and 1 more

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Dosimetry of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Pooled it
  3. Joint EANM/SNMMI procedure guideline for the use ofEuropean journal of nuclear medicine and molecular imaging · 2023
    Guideline
  4. The Prostate · 2022
    Pooled it
  5. Pooled it
  6. Third-line treatment andEuropean journal of nuclear medicine and molecular imaging · 2018
    Pooled it
  7. Article
  8. Article
  9. Article
  10. Review
  11. Leveraging [Clinical and translational science · 2026
    Article
  12. Impact of extended [European journal of nuclear medicine and molecular imaging · 2025
    Article
  13. JHU-2545 preferentially shields salivary glands and kidneys during PSMA-targeted imaging.European journal of nuclear medicine and molecular imaging · 2025
    Article
  14. Article
  15. Article
  16. Efficacy and safety of rechallenge with [European journal of nuclear medicine and molecular imaging · 2024
    Article
  17. Review
  18. Article
  19. Review
  20. A phase 1 trial to determine the maximum tolerated dose and patient-specific dosimetry of [European journal of nuclear medicine and molecular imaging · 2024
    Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lorenza ScarpaDepartment of Nuclear Medicine, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Sabine BuxbaumDepartment of Nuclear Medicine, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Dorota KendlerDepartment of Nuclear Medicine, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Katharina FinkDepartment of Nuclear Medicine, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Jasmin BekticDepartment of Urology, Medical University of Innsbruck, Innsbruck, Austria.
Leonhard GruberDepartment of Radiology, Medical University of Innsbruck, Innsbruck, Austria.
Clemens DecristoforoDepartment of Nuclear Medicine, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Christian UprimnyDepartment of Nuclear Medicine, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria.
Peter LukasDepartment of Radiotherapy / Radiation Oncology, Medical University of Innsbruck, Innsbruck, Austria.
Wolfgang HorningerDepartment of Urology, Medical University of Innsbruck, Innsbruck, Austria.
Irene VirgoliniDepartment of Nuclear Medicine, Medical University Innsbruck, Anichstraße 35, A-6020, Innsbruck, Austria. irene.virgolini@i-med.ac.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionA targeted theragnostic approach based on increased expression of prostate-specific membrane antigen (PSMA) on PC cells is an attractive treatment option for patients with metastatic castration-resistant prostate cancer (mCRPC).

methodsTen consecutive mCRPC patients were selected for

results

conclusionDue to substantial individual variance, dosimetry is mandatory for a patient-specific approach following

Indexed as

Gallium RadioisotopesRadiation DosageAgedAged, 80 and overAntigens, SurfaceEdetic AcidGene Expression Regulation, NeoplasticGlutamate Carboxypeptidase IIHumansLutetiumMaleMiddle AgedMolecular Targeted TherapyNeoplasm MetastasisPositron Emission Tomography Computed TomographyProstatic Neoplasms, Castration-ResistantAntigens, SurfaceEdetic AcidFOLH1 protein, humanGallium RadioisotopesGlutamate Carboxypeptidase IILutetiumN,N'-bis(2-hydroxy-5-(ethylene-beta-carboxy)benzyl)ethylenediamine N,N'-diacetic acid18F-NaF-PET68Ga/177 Lu-PSMA-targeted theragnostic conceptDosimetryProstate cancer

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.