ArticleWorld journal of hepatology2016
Enzyme pattern of biliary colic: A counterintuitive picture.
Article in World journal of hepatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- Spontaneous passage of common bile duct stones: predictive factors and impact on post-ERCP complications.PloS one · 2026Article
- Might be over-evaluated: Predicting choledocholithiasis in patients with acute biliary pancreatitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
- Pathophysiology of severe gallstone pancreatitis: A new paradigm.World journal of gastroenterology · 2024Article
- Win or lose, nighttime transcystic laparoscopic common bile duct exploration is a win.Trauma surgery & acute care open · 2023Article
- Gallstone Hepatitis Caused by Transient Common Bile Duct Obstruction in a Middle-Aged Woman.Cureus · 2022Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo evaluate the diagnostic value of serial biochemical blood tests in the diagnosis of biliary colic.
methodsFiles were reviewed of 1039 patients who were admitted to the Share'e Zedek Medical Center emergency department between the years 2012-2013, and received the coding of acute biliary disease. Of these, the first 100 cases were selected that met the following criteria: (1) a diagnosis of biliary colic or symptomatic cholelithiasis; (2) at least two biochemical blood tests performed; and (3) 18 years of age or older. Patients with other acute biliary diseases were excluded. The biochemical profile of the patients was analyzed as were their clinical and radiological findings.
resultsThree-quarters of the patients were women, whose average age of 37 years was younger than the average of the men, at 50 years. According to their histories, 47% of the patients had previously known cholelithiasis. Pain in either the right upper quadrant or the epigastrium was the presenting symptom in 93% cases. The greatest change in serum biochemical results was seen during the first day of the patients' admissions. Alanine aminotransferase (ALT) showed the highest initial rise above the reference range, followed by aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT), bilirubin and alkaline phosphatase (ALKP) - all these increases were statistically significant (
conclusionSerial serum liver enzyme measurements are helpful in the initial diagnosis of acute biliary colic.
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