ReviewFrontiers in endocrinology2016
GnIH Control of Feeding and Reproductive Behaviors.
Review in Frontiers in endocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 55 citations in OpenAlex.
- GnIH secreted by green light exposure, regulates bone mass through the activation of Gpr147.Bone research · 2025Article
- Variation in theAnimal biotechnology · 2024Article
- Grid1 regulates the onset of puberty in female rats.The Journal of veterinary medical science · 2024Article
- Reproduction of Awassi and Hamdani Sheep Is Associated With a Novel Missense SNP (p.24Ile>Thr) of theBioinformatics and biology insights · 2024Article
- RFRP-3 Influences Apoptosis and Steroidogenesis of Yak Cumulus Cells and Compromises Oocyte Meiotic Maturation and Subsequent Developmental Competence.International journal of molecular sciences · 2023Article
- Effects of RFRP‑3 on an ovariectomized estrogen‑primed rat model and HEC‑1A human endometrial carcinoma cells.Experimental and therapeutic medicine · 2023Article
- Impact of stress on male fertility: role of gonadotropin inhibitory hormone.Frontiers in endocrinology · 2023Review
- Variation in Hypothalamic GnIH Expression and Its Association withAnimals : an open access journal from MDPI · 2022Article
- Exogenous Melatonin Regulates Puberty and the Hypothalamic GnRH-GnIH System in Female Mice.Brain sciences · 2022Article
- Direct effect of RFRP-3 microinjection into the lateral ventricle on the hypothalamic kisspeptin neurons in ovariectomized estrogen-primed rats.Experimental and therapeutic medicine · 2022Article
- A G protein-coupled receptor mediates neuropeptide-induced oocyte maturation in the jellyfish Clytia.PLoS biology · 2020Article
- Neuroendocrinology of reproduction: Is gonadotropin-releasing hormone (GnRH) dispensable?Frontiers in neuroendocrinology · 2019Review
- The Gonadotropin-Inhibitory Hormone: What We Know and What We Still Have to Learn From Fish.Frontiers in endocrinology · 2019Review
- The roles of RFamide-related peptides (RFRPs), mammalian gonadotropin-inhibitory hormone (GnIH) orthologues in female reproduction.Iranian journal of basic medical sciences · 2018Review
- Editorial: The Roles of GnIH in Reproductive Function and Behavior.Frontiers in endocrinology · 2018Article
- How to Contribute to the Progress of Neuroendocrinology: Discovery of GnIH and Progress of GnIH Research.Frontiers in endocrinology · 2018Review
- Comparative and Evolutionary Aspects of Gonadotropin-Inhibitory Hormone and FMRFamide-Like Peptide Systems.Frontiers in neuroscience · 2018Article
- The Arg-Phe-amide peptide 26RFa/glutamine RF-amide peptide and its receptor: IUPHAR Review 24.British journal of pharmacology · 2017Review
- Gonadotropin-Inhibitory Hormone Plays Roles in Stress-Induced Reproductive Dysfunction.Frontiers in endocrinology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In 2000, Tsutsui and colleagues discovered a neuropeptide gonadotropin-inhibitory hormone (GnIH) that inhibits gonadotropin release in birds. Subsequently, extensive studies during the last 15 years have demonstrated that GnIH is a key neurohormone that regulates reproduction in vertebrates, acting in the brain and on the pituitary to modulate reproduction and reproductive behavior. On the other hand, deprivation of food and other metabolic challenges inhibit the reproductive axis as well as sexual motivation. Interestingly, recent studies have further indicated that GnIH controls feeding behavior in vertebrates, such as in birds and mammals. This review summarizes the discovery of GnIH and its conservation in vertebrates and the neuroendocrine control of feeding behavior and reproductive behavior by GnIH.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.